Evidence map›Paper›PMID 34977366›Full record

ArticleTechnical innovations & patient support in radiation oncology2022

Two compound techniques for total body irradiation.

Anders T Hansen, Hanne K Rose, Esben S Yates, Jolanta Hansen, Jørgen B B Petersen

Erratum issuedAbstract read
In one paragraph

Article in Technical innovations & patient support in radiation oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Anders T HansenDepartment of Medical Physics, Aarhus University Hospital, Aarhus, Denmark.
Hanne K RoseDepartment of Oncology, Aarhus University Hospital, Aarhus, Denmark.
Esben S YatesDepartment of Medical Physics, Aarhus University Hospital, Aarhus, Denmark.
Jolanta HansenDepartment of Medical Physics, Aarhus University Hospital, Aarhus, Denmark.
Jørgen B B PetersenDepartment of Medical Physics, Aarhus University Hospital, Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTotal body irradiation (TBI) is an important treatment modality that is used in combination with chemotherapy in many stem cell transplantation protocols. Therefore, the quality of the irradiation is important. Two techniques for planning and delivering TBI are presented and compared. METHODS AND MATERIALS: The technique named ExIMRT is a combination of manually shaped conventional fields from an extended SSD and isocentric IMRT fields. The technique named ExVMAT is a combination of conventional and IMRT fields from an extended SSD and isocentric VMAT fields. Dosimetric data from 32 patients who were planned and treated according to one of the two techniques were compared.

resultsWhen comparing the two techniques, it is determined that the ExVMAT technique is able to significantly reduce the mean total volume overdosed by 120% from 408 to 12 cm

conclusionUsing the ExVMAT technique, a superior dose distribution can be delivered both from a patient and a population perspective compared to the ExIMRT technique.

Indexed as

IMRTRILITotal body irradiationTreatment planningVMAT

Identifiers

PMID34977366
PMCPMC8683645

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.