ArticleArthroplasty today2022
Increased Prevalence of Depressive Symptoms in Patients Undergoing Revision for Periprosthetic Joint Infection.
Article in Arthroplasty today, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biopsychosocial needs and complementary treatments for patients undergoing management for periprosthetic joint infection following hip or knee arthroplasty: a systematic review.EFORT open reviews · 2026Pooled it
- Extended Oral Antibiotics After Primary Total Hip and Knee Arthroplasty in an Ambulatory Surgery Center: A Bayesian Threshold and Cost-Effectiveness Analysis.Arthroplasty today · 2026Article
- A Comparison of Health-Related Quality of Life in Patients with Periprosthetic Joint Infection, Patients with Fracture-Related Infections and the General Population-A Multicenter Analysis of 384 Patients from the Section "Musculoskeletal Infections" of the German Society for Orthopaedics and Traumatology.Journal of clinical medicine · 2025Article
- The PJI-TNM Classification as Predictor for Revision-Free Implant Survival Rates in Patients with Periprosthetic Joint Infection of the Hip or Knee Joint.Infectious disease reports · 2025Article
- Prevalence of Depressive Symptoms in Patients Undergoing Aseptic Revision Total Hip Arthroplasty Differs Based on Mode of Failure.Arthroplasty today · 2025Article
- Periprosthetic Joint Infection: A Multifaceted Burden Undermining Arthroplasty Success.Orthopedic reviews · 2025Article
- Impact of Perioperative Dexamethasone Administration on Infection and Implant Osseointegration in a Preclinical Model of Orthopedic Device-Related Infection.Microorganisms · 2024Article
- The Effect of Spacer Treatment of Infected Hip and Knee Arthroplasties on Patients' Mental Health: A Narrative Review of the Literature.Healthcare (Basel, Switzerland) · 2024Review
- A Pilot Study Using a Standardized Method of Measuring Distress Demonstrates Higher Levels in Septic Revisions.Arthroplasty today · 2023Article
- No difference in bacterial contamination of hip capsule sutures and control sutures in hip arthroplasty surgery.Antimicrobial resistance and infection control · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeriprosthetic joint infection (PJI) is a devastating complication after total joint arthroplasty. Patients undergoing revision for PJI may experience psychological distress and symptoms of depression, both of which are linked to poor postoperative outcomes. We, therefore, aim to identify the prevalence of depression and depressive symptoms in patients before treatment for PJI and their link to functional outcomes.
methodsPatients undergoing either debridement with implant retention (DAIR) or 2-stage exchange for PJI with minimum 1-year follow-up were retrospectively reviewed. The 2-stage (n = 37) and single-stage (n = 39) patients that met inclusion criteria were matched based off age (±5 years), gender, and body mass index (±5) to patients undergoing aseptic revisions. Outcomes evaluated included a preoperative diagnosis of clinical depression and preoperative and postoperative Veterans RAND 12 Item Health Survey mental component score and physical component score.
resultsCompared to matched controls, the prevalence of depressive symptoms was significantly greater in patients undergoing 2-stage exchange preoperatively (40.5% vs 10.8%,
conclusionsPatients undergoing 2-stage exchange for PJI have a four times higher prevalence of preoperative depressive symptoms than patients undergoing aseptic revision. Patients undergoing DAIR with depression or preoperative depressive symptoms have lower functional scores postoperatively. Orthopedic surgeon screening of PJI patients with referral for treatment of depression may help improve outcomes postoperatively.
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