Evidence map›Paper›PMID 34977272›Full record

ArticleMolecular therapy. Methods & clinical development2022

miRNA-mediated control of exogenous

Ramya Rallabandi, Brenna Sharp, Conrad Cruz, Qi Wang, Alexis Locsin, Christopher B Driscoll, Ella Lee, Tim Nelson, Patricia Devaux

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Engineering single-cycle MeV vector for CRISPR-Cas9 gene editing.Molecular therapy. Methods & clinical development · 2024
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ramya RallabandiVirology and Gene Therapy Graduate Track, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Brenna SharpDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Conrad CruzDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Qi WangDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Alexis LocsinDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Christopher B DriscollVirology and Gene Therapy Graduate Track, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic, Rochester, MN 55905, USA.
Ella LeeDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Tim NelsonDepartment of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester MN 55905, USA.
Patricia DevauxDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Mayo Clinic in Arizona · USMayo Clinic · US

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI AKHILESH PANDEY · 1985 to 2026
$151.3M
PhD Training Program in Virology and Gene TherapyT32AI132165 · NIAID · MAYO CLINIC ROCHESTER · PI ROBERTO B. CATTANEO · 2018 to 2026
$1.3M
Single non-integrating RNA vector for gene editing and reprogramming of Fanconi anemia fibroblastsR01HL147852 · NHLBI · MAYO CLINIC ROCHESTER · PI DEVAUX, PATRICIA · 2020 to 2022
$954k
Measles vectors for genomic modification-free induced pluripotent stem cellsR21AI105233 · NIAID · MAYO CLINIC ROCHESTER · PI DEVAUX, PATRICIA · 2013 to 2014
$437k
Single non-integrating RNA vector for gene editing and reprogramming of Fanconi anemia fibroblastsR56HL147852 · NHLBI · MAYO CLINIC ROCHESTER · PI DEVAUX, PATRICIA · 2019 to 2019
$318k
NCI NIH HHS P30 CA015083NHLBI NIH HHS R01 HL147852NHLBI NIH HHS R56 HL147852NIAID NIH HHS R21 AI105233NIAID NIH HHS T32 AI132165
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

iPSCmeasles virusmesenchymal-epithelial transitionmicroRNA targetingOCT4reprogrammingviral vectors

Identifiers

PMID34977272
PMCPMC8683617
OpenAlexW3215055369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.