Evidence map›Paper›PMID 34977234›Full record

ArticleBioMed research international2021

Imaging Tool for Predicting Renal Clear Cell Carcinoma Fuhrman Grade: Comparing R.E.N.A.L. Nephrometry Score and CT Texture Analysis.

Ran Sun, Sheng Zhao, Huijie Jiang, Hao Jiang, Yanmei Dai, Chuzhen Zhang, Song Wang

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. CT-based AI score associates with perioperative outcomes in nephron-sparing surgery for renal cell carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ran SunDepartment of Radiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Sheng ZhaoDepartment of Radiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Huijie JiangDepartment of Radiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.ORCID https://orcid.org/0000-0001-7321-5297
Hao JiangDepartment of Radiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Yanmei DaiDepartment of Radiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Chuzhen ZhangDepartment of Radiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Song WangDepartment of Radiology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, China.ORCID https://orcid.org/0000-0001-9583-4240
Harbin Medical University · CNShanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClear cell renal cell carcinoma (ccRCC) is the most common renal malignant tumor. Preoperative imaging boasts advantages in diagnosing and choosing treatment methods for ccRCC. PURPOSE: This study is aimed at building models based on R.E.N.A.L. nephrometry score (RNS) and CT texture analysis (CTTA) to estimate the Fuhrman grade of ccRCC and comparing the advantages and disadvantages of the two models. MATERIALS AND

methods143 patients with pathologically confirmed ccRCC were enrolled. All patients were stratified into Fuhrman low-grade and high-grade groups with complete CT data and R.E.N.A.L. nephrometry scores. CTTA features were extracted from the ROI delineated at the largest tumor level, and RNS and CTTA features were included in the logistic regression model, respectively.

resultsRNS model constructed based on multivariate logistic regression analysis showed that 3 pts for

conclusionsR.E.N.A.L. nephrometry score has a certain provocative effect on the Fuhrman pathological grading of ccRCC. As a potential emerging technology, CTTA is expected to replace R.E.N.A.L. nephrometry score in evaluating patients' Fuhrman classification, and this approach might become an available method for assisting clinicians in choosing appropriate operation.

Indexed as

Carcinoma, Renal CellDiagnosis, DifferentialFemaleHumansKidneyKidney NeoplasmsLogistic ModelsMaleMiddle AgedNeoplasm GradingRetrospective StudiesROC CurveSensitivity and SpecificityTomography, X-Ray Computed

Identifiers

PMID34977234
PMCPMC8718284
OpenAlexW4200027588

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.