Evidence map›Paper›PMID 34976986›Full record

ReviewFrontiers in bioengineering and biotechnology2021

Recent Advances in Metal-Organic Framework-Based Electrochemical Biosensing Applications.

Mengjie Li, Guangyao Zhang, Andrews Boakye, Huining Chai, Lijun Qu, Xueji Zhang

Erratum issuedAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. The MOF-Microbiome Axis: a New Paradigm for Precision Nanomedicine.Probiotics and antimicrobial proteins · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Mengjie LiState Key Laboratory of Bio-Fibers and Eco-Textiles, Intelligent Wearable Engineering Research Center of Qingdao, Research Center for Intelligent and Wearable Technology, College of Textiles and Clothing, Qingdao University, Qingdao, China.
Guangyao ZhangState Key Laboratory of Bio-Fibers and Eco-Textiles, Intelligent Wearable Engineering Research Center of Qingdao, Research Center for Intelligent and Wearable Technology, College of Textiles and Clothing, Qingdao University, Qingdao, China.
Andrews BoakyeState Key Laboratory of Bio-Fibers and Eco-Textiles, Intelligent Wearable Engineering Research Center of Qingdao, Research Center for Intelligent and Wearable Technology, College of Textiles and Clothing, Qingdao University, Qingdao, China.
Huining ChaiSchool of Environmental and Municipal Engineering, Qingdao University of Technology, Qingdao, China.
Lijun QuState Key Laboratory of Bio-Fibers and Eco-Textiles, Intelligent Wearable Engineering Research Center of Qingdao, Research Center for Intelligent and Wearable Technology, College of Textiles and Clothing, Qingdao University, Qingdao, China.
Xueji ZhangSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the face of complex environments, considerable effort has been made to accomplish sensitive, accurate and highly-effective detection of target analytes. Given the versatility of metal clusters and ligands, high porosity and large specific surface area, metal-organic framework (MOF) provides researchers with prospective solutions for the construction of biosensing platforms. Combined with the benefits of electrochemistry method such as fast response, low cost and simple operation, the untapped applications of MOF for biosensors are worthy to be exploited. Therefore, this review briefly summarizes the preparation methods of electroactive MOF, including synthesize with electroactive ligands/metal ions, functionalization of MOF with biomolecules and modification for MOF composites. Moreover, recent biosensing applications are highlighted in terms of small biomolecules, biomacromolecules, and pathogenic cells. We conclude with a discussion of future challenges and prospects in the field. It aims to offer researchers inspiration to address the issues appropriately in further investigations.

Indexed as

biomacromoleculeselectrochemical biosensingmetal-organic frameworkpathogenic cellssmall biomolecules

Identifiers

PMID34976986
PMCPMC8716788

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.