Evidence map›Paper›PMID 34976954›Full record

ReviewFrontiers in chemistry2021

The Advance of CRISPR-Cas9-Based and NIR/CRISPR-Cas9-Based Imaging System.

Huanhuan Qiao, Jieting Wu, Xiaodong Zhang, Jian Luo, Hao Wang, Dong Ming

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. CRISPR/Cas9 Landscape: Current State and Future Perspectives.International journal of molecular sciences · 2023
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huanhuan QiaoFunctional Materials Laboratory, Institute of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Jieting WuFunctional Materials Laboratory, Institute of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Xiaodong ZhangFunctional Materials Laboratory, Institute of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Jian LuoPalo Alto Veterans Institute for Research, VA Palo Alto Health Care System, Palo Alto, CA, United States.
Hao WangFunctional Materials Laboratory, Institute of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Dong MingFunctional Materials Laboratory, Institute of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study of different genes, chromosomes and the spatiotemporal relationship between them is of great significance in the field of biomedicine. CRISPR-Cas9 has become the most widely used gene editing tool due to its excellent targeting ability. In recent years, a series of advanced imaging technologies based on Cas9 have been reported, providing fast and convenient tools for studying the sites location of genome, RNA, and chromatin. At the same time, a variety of CRISPR-Cas9-based imaging systems have been developed, which are widely used in real-time multi-site imaging

Indexed as

CRISPR-Cas9CRISPR-Cas9-based imaging systemNIR/CRISPR-Cas9-based imaging systemNIR fluorophoresNIR imaging

Identifiers

PMID34976954
PMCPMC8716450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.