Evidence map›Paper›PMID 34976862›Full record

ArticleFrontiers in cellular and infection microbiology2021

Differentially Expressed Extracellular Vesicle, Exosome and Non-Exosome miRNA Profile in High and Low Tick-Resistant Beef Cattle.

Pevindu Abeysinghe, Natalie Turner, Hassendrini Peiris, Kanchan Vaswani, Nick Cameron, Nathanael McGhee, Jayden Logan, Murray D Mitchell

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Pevindu AbeysingheCentre for Children's Health Research, School of Biomedical Sciences, Faculty of Health, The Queensland University of Technology, Brisbane, QLD, Australia.
Natalie TurnerCentre for Children's Health Research, School of Biomedical Sciences, Faculty of Health, The Queensland University of Technology, Brisbane, QLD, Australia.
Hassendrini PeirisCentre for Children's Health Research, School of Biomedical Sciences, Faculty of Health, The Queensland University of Technology, Brisbane, QLD, Australia.
Kanchan VaswaniCentre for Children's Health Research, School of Biomedical Sciences, Faculty of Health, The Queensland University of Technology, Brisbane, QLD, Australia.
Nick CameronNindooinbah Pastoral Company, Nindooinbah, QLD, Australia.
Nathanael McGheeNindooinbah Pastoral Company, Nindooinbah, QLD, Australia.
Jayden LoganCentre for Children's Health Research, School of Biomedical Sciences, Faculty of Health, The Queensland University of Technology, Brisbane, QLD, Australia.
Murray D MitchellCentre for Children's Health Research, School of Biomedical Sciences, Faculty of Health, The Queensland University of Technology, Brisbane, QLD, Australia.
Queensland University of Technology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heavy tick burden on beef cattle account for huge economic losses globally, with an estimated value of US$22-30 billion per annum. In Australia, ticks cost the northern beef industry approximately A$170-200 million. Methods to evaluate and predict tick resistance would therefore be of great value to the global cattle trade. Exosomes (EX) are small extracellular vesicles (EVs) of ~30-150nm diameter and have gained popularity for their diagnostic and prognostic potential. EX contain, among other biomolecules, various types of RNA including micro-RNA (miRNA) and long noncoding RNA (lncRNA). MiRNA specifically have been validated as therapeutic biomarkers as they perform regulatory functions at the post-transcriptional level and are differentially expressed between divergent groups. The objective of the present study was to evaluate the miRNA profiles of EV and fractionated exosomal samples of high and low tick-resistant beef cattle to highlight potential miRNA biomarkers of tick resistance. Cows (

Indexed as

ExosomesExtracellular VesiclesMicroRNAsTicksAnimalsBiomarkersCattleFemaleBiomarkersMicroRNAsbeef cattleexosomeextracellular vesiclesmiRNAtick

Identifiers

PMID34976862
PMCPMC8718928
OpenAlexW4225713732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.