Evidence map›Paper›PMID 34976591›Full record

ArticleNanotheranostics2022

Development of CD44E/s dual-targeting DNA aptamer as nanoprobe to deliver treatment in hepatocellular carcinoma.

Cario Wing-Sze Lo, Cecilia Ka Wing Chan, Jianqing Yu, Mian He, Chung Hang Jonathan Choi, James Yun Wong Lau, Nathalie Wong

Open access · goldAbstract read
In one paragraph

Article in Nanotheranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Revealing the role of SPP1Cell & bioscience · 2024
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cario Wing-Sze LoDepartment of Surgery at Sir Y.K. Pao Center for Cancer, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
Cecilia Ka Wing ChanDepartment of Surgery at Sir Y.K. Pao Center for Cancer, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
Jianqing YuDepartment of Surgery at Sir Y.K. Pao Center for Cancer, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
Mian HeScience Research Center, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen 518107, China.
Chung Hang Jonathan ChoiDepartment of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
James Yun Wong LauDepartment of Surgery at Sir Y.K. Pao Center for Cancer, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
Nathalie WongDepartment of Surgery at Sir Y.K. Pao Center for Cancer, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
Chinese University of Hong Kong · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Aptamers, NucleotideCarcinoma, HepatocellularLiver NeoplasmsAnimalsCell ProliferationHumansTissue DistributionAptamers, NucleotideaptamerCD44hepatocellular carcinomananoprobetargeted cancer therapy

Identifiers

PMID34976591
PMCPMC8671951
OpenAlexW3208817774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.