ArticleChemical science2021
Skeletal remodeling of chalcone-based pyridinium salts to access isoindoline polycycles and their bridged derivatives.
Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 44 citations in OpenAlex.
- Recent Strategies in the Nucleophilic Dearomatization of Pyridines, Quinolines, and Isoquinolines.Chemical reviews · 2024Review
- First-row transition metal for isocyanide-involving multicomponent reactions (IMCR).Molecular diversity · 2023Review
- Construction ofMolecules (Basel, Switzerland) · 2023Article
- Streptocyanine as an activation mode of amine catalysis for the conversion of pyridine rings to benzene rings.Chemical science · 2023Article
- Recent progress in the chemistry of β-aminoketones.RSC advances · 2022Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Simultaneous deconstructive ring-opening and skeletal reconstruction of an inert, aromatic pyridinium ring is of great importance in synthetic communities. However, research in this area is still in its infancy. Here, a skeletal re-modeling strategy was developed to transform chalcone-based pyridinium salts into structurally intriguing polycyclic isoindolines through a dearomative ring-opening/ring-closing sequence. Two distinct driving forces for the deconstruction of the pyridinium core were involved in these transformations. One was the unprecedented harnessing of the instability of
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Registered trials
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