Evidence map›Paper›PMID 34976358›Full record

ArticleChemical science2021

Luminol anchors improve the electrochemical-tyrosine-click labelling of proteins.

Sébastien Depienne, Dimitri Alvarez-Dorta, Mikael Croyal, Ranil C T Temgoua, Cathy Charlier, David Deniaud, Mathieu Mével, Mohammed Boujtita, Sébastien G Gouin

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Biocompatible Chemistry: A Plug-and-Play Toolbox for Chemical Biology Research.Chembiochem : a European journal of chemical biology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Chemical Conjugation to Less Targeted Proteinogenic Amino Acids.Chembiochem : a European journal of chemical biology · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sébastien DepienneUniversité de Nantes, CNRS, CEISAM UMR 6230 F-44000 Nantes France sebastien.gouin@univ-nantes.fr sebastien.depienne@univ-nantes.fr.
Dimitri Alvarez-DortaUniversité de Nantes, CNRS, CEISAM UMR 6230 F-44000 Nantes France sebastien.gouin@univ-nantes.fr sebastien.depienne@univ-nantes.fr.
Mikael CroyalUniversité de Nantes, CNRS, INSERM, L'institut du Thorax F-44000 Nantes France.
Ranil C T TemgouaUniversité de Nantes, CNRS, CEISAM UMR 6230 F-44000 Nantes France sebastien.gouin@univ-nantes.fr sebastien.depienne@univ-nantes.fr.ORCID https://orcid.org/0000-0003-1876-2962
Cathy CharlierIMPACT Platform, Interactions Moléculaires Puces ACTivités, UMR CNRS 6286 UFIP, Université de Nantes F-44000 Nantes France.
David DeniaudUniversité de Nantes, CNRS, CEISAM UMR 6230 F-44000 Nantes France sebastien.gouin@univ-nantes.fr sebastien.depienne@univ-nantes.fr.ORCID https://orcid.org/0000-0002-0846-1798
Mathieu MévelUniversité de Nantes, CNRS, CEISAM UMR 6230 F-44000 Nantes France sebastien.gouin@univ-nantes.fr sebastien.depienne@univ-nantes.fr.ORCID https://orcid.org/0000-0002-6070-2755
Mohammed BoujtitaUniversité de Nantes, CNRS, CEISAM UMR 6230 F-44000 Nantes France sebastien.gouin@univ-nantes.fr sebastien.depienne@univ-nantes.fr.
Sébastien G GouinUniversité de Nantes, CNRS, CEISAM UMR 6230 F-44000 Nantes France sebastien.gouin@univ-nantes.fr sebastien.depienne@univ-nantes.fr.ORCID https://orcid.org/0000-0002-0985-1165
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New methods for chemo-selective modifications of peptides and native proteins are important in chemical biology and for the development of therapeutic conjugates. Less abundant and uncharged amino-acid residues are interesting targets to form less heterogeneous conjugates and preserve biological functions. Phenylurazole (PhUr),

Identifiers

PMID34976358
PMCPMC8635215
OpenAlexW3214513338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.