Evidence map›Paper›PMID 34976343›Full record

ArticleChemical science2021

Dynamic supramolecular self-assembly of platinum(ii) complexes perturbs an autophagy-lysosomal system and triggers cancer cell death.

Ka-Chung Tong, Pui-Ki Wan, Chun-Nam Lok, Chi-Ming Che

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Chemical science · 2023
    Article
  9. Supramolecular platinum complexes for cancer therapy.Current opinion in chemical biology · 2023
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Ka-Chung TongState Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong Pokfulam Road Hong Kong China cmche@hku.hk.
Pui-Ki WanState Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong Pokfulam Road Hong Kong China cmche@hku.hk.
Chun-Nam LokState Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong Pokfulam Road Hong Kong China cmche@hku.hk.ORCID https://orcid.org/0000-0001-9473-968X
Chi-Ming CheState Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong Pokfulam Road Hong Kong China cmche@hku.hk.ORCID https://orcid.org/0000-0002-2554-7219
State Key Laboratory of Synthetic Chemistry · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Self-assembly of platinum(ii) complexes to form supramolecular structures/nanostructures due to intermolecular ligand π-π stacking and metal-ligand dispersive interactions is widely used to develop functional molecular materials, but the application of such non-covalent molecular interactions has scarcely been explored in medical science. Herein is described the unprecedented biological properties of platinum(ii) complexes relevant to induction of cancer cell death

Identifiers

PMID34976343
PMCPMC8635173
OpenAlexW3203303613

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.