Evidence map›Paper›PMID 34976311›Full record

ArticleComputational and structural biotechnology journal2022

Dynamics of hydrogen bonds in the secondary structures of allosteric protein

Mayar Tarek Ibrahim, Francesco Trozzi, Peng Tao

Abstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Markov State Models: To Optimize or Not to Optimize.Journal of chemical theory and computation · 2024
    Article
  6. Article
  7. Article
  8. Novel Allosteric Effectors Targeting Human Transcription Factor TEAD.International journal of molecular sciences · 2023
    Article
  9. Article
  10. Machine learning and protein allostery.Trends in biochemical sciences · 2023
    Review
  11. Allosteric regulation of autoinhibition and activation of c-Abl.Computational and structural biotechnology journal · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mayar Tarek IbrahimDepartment of Chemistry, Center for Research Computing, Center for Drug Discovery, Design, and Delivery (CD4), Southern Methodist University, Dallas, Texas, United States.
Francesco TrozziDepartment of Chemistry, Center for Research Computing, Center for Drug Discovery, Design, and Delivery (CD4), Southern Methodist University, Dallas, Texas, United States.
Peng TaoDepartment of Chemistry, Center for Research Computing, Center for Drug Discovery, Design, and Delivery (CD4), Southern Methodist University, Dallas, Texas, United States.

Funding

Probing Hidden Conformational Space and Dynamical States of Circadian Clock Proteins through Rigid Residue Scan and Machine LearningR15GM122013 · NIGMS · SOUTHERN METHODIST UNIVERSITY · PI TAO, PENG · 2018 to 2023
$800k
NIGMS NIH HHS R15 GM122013
6 · The paper itself

Abstract

The Light-Oxygen-Voltage 2 (LOV2) domain of

Indexed as

AllosteryAsLOV2Hydrogen bond networkLOV domainMachine learning

Identifiers

PMID34976311
PMCPMC8671528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.