Evidence map›Paper›PMID 34976218›Full record

ArticleTheranostics2022

5-aza-2'-deoxycytidine potentiates anti-tumor immunity in colorectal peritoneal metastasis by modulating ABC A9-mediated cholesterol accumulation in macrophages.

Rongchen Shi, Kun Zhao, Teng Wang, Jing Yuan, Dapeng Zhang, Wei Xiang, Jin Qian, Na Luo, Yong Zhou, Bo Tang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 44 citations in OpenAlex.

  1. Macrophage PABPC4-SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  11. Abnormal changes in metabolites caused by mJournal of advanced research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Rongchen ShiDepartment of Biochemistry and Molecular Biology, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Kun ZhaoDepartment of Biochemistry and Molecular Biology, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Teng WangDepartment of Biochemistry and Molecular Biology, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Jing YuanDepartment of Biochemistry and Molecular Biology, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Dapeng ZhangDepartment of Biochemistry and Molecular Biology, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Wei XiangDepartment of Biochemistry and Molecular Biology, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Jin QianDepartment of Biochemistry and Molecular Biology, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Na LuoDepartment of Biochemistry and Molecular Biology, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Yong ZhouChongqing Weisiteng Biotech Translational Research Institute, Chongqing 400039, China.
Bo TangDepartment of General Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Chuan LiDepartment of General Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Hongming MiaoDepartment of Biochemistry and Molecular Biology, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Army Medical University · CNSouthwest Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntimetabolites, AntineoplasticCholesterolColorectal NeoplasmsDecitabineDNA Modification MethylasesEnzyme InhibitorsHumansMacrophages, PeritonealMaleMiceMice, Inbred BALB CMice, Inbred C57BLNeoplasm MetastasisPeritoneal NeoplasmsTumor MicroenvironmentAntimetabolites, AntineoplasticCholesterolDecitabineDNA Modification MethylasesEnzyme Inhibitors5AzaABC A9CRC-PCIL-6macrophages

Identifiers

PMID34976218
PMCPMC8692916
OpenAlexW4200590334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.