Evidence map›Paper›PMID 34976103›Full record

ArticleComputational and mathematical methods in medicine2021

Enriched Environment Regulates Dendritic Cells to Alleviate Inflammation in Cerebral Infarction Lesions.

Zhenzhen Zhong, Ping Xu, Jun Wen, Xiangdong Li, Xiaobo Zhang

RetractedOpen access · hybridAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Computational and mathematical methods in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhenzhen ZhongDepartment of Neurology, The First People's Hospital of Changde City, Changde, Hunan, China 415000.ORCID https://orcid.org/0000-0003-4059-7203
Ping XuDepartment of Neurology, The First People's Hospital of Changde City, Changde, Hunan, China 415000.
Jun WenDepartment of Neurology, The First People's Hospital of Changde City, Changde, Hunan, China 415000.
Xiangdong LiDepartment of Neurology, The First People's Hospital of Changde City, Changde, Hunan, China 415000.
Xiaobo ZhangDepartment of Neurology, The First People's Hospital of Changde City, Changde, Hunan, China 415000.
The First People's Hospital of Changde · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim was to investigate the role that enriched environment (EE) plays in the regulation of inflammation in cerebral infarction (CI) lesions and further explore the relationship between this regulation and dendritic cells (DCs).

methods72 Sprague-Dawley rats were randomly divided into sham operation group (CON group,

resultsIn comparison with the CON group, the NC and EE groups showed significant increases in neuronal injury, CD74- and Integrin

conclusionEE avoids the accumulation of DCs in the lesions and reduces the contents of IL-1

Indexed as

Animal HusbandryAnimalsBehavior, AnimalBrainCerebral InfarctionComputational BiologyCytokinesDendritic CellsDisease Models, AnimalEnvironmentInflammation MediatorsMaleNeuronsRatsRats, Sprague-DawleyCytokinesInflammation Mediators

Identifiers

PMID34976103
PMCPMC8719993
OpenAlexW4200570274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.