Evidence map›Paper›PMID 34975875›Full record

ReviewFrontiers in immunology2021

Medawar's PostEra: Galectins Emerged as Key Players During Fetal-Maternal Glycoimmune Adaptation.

Ellen Menkhorst, Nandor Gabor Than, Udo Jeschke, Gabriela Barrientos, Laszlo Szereday, Gabriela Dveksler, Sandra M Blois

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 22 citations in OpenAlex.

  1. Insights into Reproductive Immunology and Placental Pathology, 2nd Edition.International journal of molecular sciences · 2026
    Article
  2. Article
  3. Review
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  5. Review
  6. Article
  7. Article
  8. Review
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  10. Review
  11. Article
  12. Review
  13. Pre-eclampsia.Nature reviews. Disease primers · 2023
    Review
  14. Review
  15. Review
  16. Article
  17. Seminal Plasma Glycoproteins as Potential Ligands of Lectins Engaged in Immunity Regulation.International journal of environmental research and public health · 2022
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 5 countries.

Ellen MenkhorstDepartment of Obstetrics and Gynaecology, University of Melbourne, Melbourne, VIC, Australia.
Nandor Gabor ThanSystems Biology of Reproduction Research Group, Institute of Enyzmology, Research Centre for Natural Sciences, Budapest, Hungary.
Udo JeschkeDepartment of Obstetrics and Gynecology, University Hospital Augsburg, Augsburg, Germany.
Gabriela BarrientosLaboratorio de Medicina Experimental, Hospital Alemán-Consejo Nacional de Investigaciones Científicas y Técnicas, Ciudad Autónoma de Buenos Aires, Argentina.
Laszlo SzeredayMedical School, Department of Medical Microbiology and Immunology, University of Pecs, Pecs, Hungary.
Gabriela DvekslerDepartment of Pathology, Uniformed Services University, Bethesda, MD, United States.
Sandra M BloisDepartment of Obstetrics and Fetal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Hospital Alemán · ARInstitute of Molecular Life Sciences · HUUniformed Services University of the Health Sciences · USUniversität Hamburg · DEUniversity Hospital Augsburg · DEUniversity of Melbourne · AUUniversity of Pecs · HU

Funding

Interaction of Galectin-9 and Pregnancy-Specific Glycoprotein 1 in the Regulation of Cells of the Innate and Adaptive Immune SystemR21AI156058 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI DVEKSLER, GABRIELA S · 2021 to 2022
$419k
NIAID NIH HHS R21 AI156058
6 · The paper itself

Abstract

Lectin-glycan interactions, in particular those mediated by the galectin family, regulate many processes required for a successful pregnancy. Over the past decades, increasing evidence gathered from

Indexed as

Adaptation, PhysiologicalFemaleFetal DevelopmentGalectinsGlycoproteinsHumansPlacentationPregnancyGalectinsGlycoproteinsgalectinsglycoimmunologyplacentapregnancypregnancy specific proteins

Identifiers

PMID34975875
PMCPMC8715898
OpenAlexW4200318483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.