Evidence map›Paper›PMID 34975862›Full record

Observational studyFrontiers in immunology2021

A Role for B Cells to Transmit Hepatitis C Virus Infection.

Isabelle Desombere, Freya Van Houtte, Ali Farhoudi, Lieven Verhoye, Caroline Buysschaert, Yvonne Gijbels, Sibyl Couvent, Wilfried Swinnen, Hans Van Vlierberghe, André Elewaut and 5 more

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Isabelle DesombereDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium.
Freya Van HoutteDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium.
Ali FarhoudiDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium.
Lieven VerhoyeDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium.
Caroline BuysschaertDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium.
Yvonne GijbelsDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium.
Sibyl CouventDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium.
Wilfried SwinnenMedisch Sociaal Opvangcentrum (MSOC) Gent, Ghent, Belgium.
Hans Van VlierbergheDepartment of Hepatology and Gastroenterology, Ghent University Hospital, Ghent, Belgium.
André ElewautDepartment of Hepatology and Gastroenterology, Ghent University Hospital, Ghent, Belgium.
Andrea MagriNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Zania StamatakiInstitute of Immunology and Immunotherapy, Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, United Kingdom.
Philip MeulemanDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium.
Jane A McKeatingNuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Geert Leroux-RoelsDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium.
Ghent University · BEGhent University Hospital · BEUniversity of Oxford · GBUniversity of Birmingham · GB

Funding

Medical Research Council MR/R022011/1MRF_ MRF-169-0001-F-STAM-C0826Wellcome TrustWellcome Trust 200838/Z/16/Z
6 · The paper itself

Abstract

Hepatitis C virus (HCV) is highly variable and transmits through infected blood to establish a chronic liver infection in the majority of patients. Our knowledge on the infectivity of clinical HCV strains is hampered by the lack of

Indexed as

AdultAnimalsAntibodies, ViralB-LymphocytesBroadly Neutralizing AntibodiesDisease Models, AnimalFemaleHepacivirusHepatitis CHumansLiverLiver TransplantationMaleMiceMiddle AgedSerumAntibodies, ViralBroadly Neutralizing AntibodiesViral Envelope ProteinsViral Hepatitis VaccinesB cellhepatitis C virusimmune responseinfectionpersistencetransmission

Identifiers

PMID34975862
PMCPMC8716873
OpenAlexW4200022472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.