Evidence map›Paper›PMID 34975736›Full record

ArticleFrontiers in neurology2021

"ET Plus": Instability of the Diagnosis During Prospective Longitudinal Follow-up of Essential Tremor Cases.

Daniella Iglesias-Hernandez, Nikki Delgado, Margaret McGurn, Edward D Huey, Stephanie Cosentino, Elan D Louis

Abstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Pathophysiological Role of Primary Motor Cortex in Essential Tremor.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  7. Article
  8. Article
  9. Associations Between Cognitive Profiles and Balance in Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025
    Article
  10. Article
  11. Clinical and kinematic characterization of parkinsonian soft signs in essential tremor.Journal of neural transmission (Vienna, Austria : 1996) · 2024
    Article
  12. Six Myths and Misconceptions about Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. The Italian tremor Network (TITAN): rationale, design and preliminary findings.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  18. Essential tremor plus rest tremor: current concepts and controversies.Journal of neural transmission (Vienna, Austria : 1996) · 2022
    Review
  19. Observational
  20. Milestones in Tremor Research: 10 Years Later.Movement disorders clinical practice · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniella Iglesias-HernandezDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Nikki DelgadoDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Margaret McGurnDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Edward D HueyDepartment of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, United States.
Stephanie CosentinoDepartment of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, United States.
Elan D LouisDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, United States.

Funding

National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8M
Research Education CoreP30AG066462 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PHILIP L DE JAGER · 2020 to 2026
$30.1M
Clinical Pathological Study of Cognitive Impairment in Essential TremorR01NS086736 · NINDS · YALE UNIVERSITY · PI COSENTINO, STEPHANIE ANN, LOUIS, ELAN D · 2014 to 2023
$8.1M
Neuroanatomical associations with the factor structure underlying neuropsychiatric symptoms in Alzheimer's diseaseR01AG062268 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HUEY, EDWARD D · 2018 to 2022
$2.5M
Using RDoC Negative and Positive Valence Paradigms to Investigate the Mechanisms of Neuropsychiatric Symptoms (NPS) in Alzheimer's Disease and Related DementiasR01MH120794 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HUEY, EDWARD D · 2019 to 2023
$2.1M
NIA NIH HHS P30 AG066462NIA NIH HHS R01 AG062268NIA NIH HHS U24 AG021886NIMH NIH HHS R01 MH120794NINDS NIH HHS R01 NS086736
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

classificationclinicaldiagnosisessential tremorET plus

Identifiers

PMID34975736
PMCPMC8716461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.