ReviewFrontiers in psychology2021
Cognitive Frailty: An Update.
Review in Frontiers in psychology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- The current state and development trends of frailty research in diabetic patients: a bibliometric analysis.Frontiers in medicine · 2025Pooled it
- Impact of multicomponent exercise and nutritional supplement interventions for improving physical frailty in community-dwelling older adults: a systematic review and meta-analysis.BMC geriatrics · 2024Pooled it
- Prevalence of cognitive frailty among older adults in China: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- Effects of different modes of computerised cognitive training in older adults with reversible cognitive frailty: a randomised controlled trial in nursing homes.BMC neurology · 2026Trial
- Effects of an educational intervention on frailty status, physical function, physical activity, sleep patterns, and nutritional status of older adults with frailty or pre-frailty: the FRAGSALUD study.Frontiers in public health · 2023Trial
- Frailty assessment in naturally aged mouse models: classification, limitations, and future directions.GeroScience · 2026Review
- Multidimensional Frailty and Resilience in Relation to Quality of Life in Senior Patients with Cardiovascular Disease: An Exploratory Cross-Sectional Pilot Study.Journal of clinical medicine · 2026Article
- Identifying potential drug targets for physical and cognitive frailty: an integrative analysis of CHARLS cohort, mendelian randomization, and gene colocalization.Biogerontology · 2026Article
- Machine learning-based prediction model for cognitive frailty in elderly patients with ischaemic stroke: a prospective cohort study.Frontiers in neurology · 2026Article
- Development and validation of a prediction model for long-term cognitive frailty risk in stroke patients based on CHARLS data.PloS one · 2026Article
- Comparison of the frailty phenotype and frailty index for identifying vulnerable companion dogs.Scientific reports · 2025Article
- Frailty Status and Dysphagia Trajectory Among Hospitalized Nursing Home Residents With Advanced Dementia.Journal of the American Medical Directors Association · 2025Article
- Prevalence and associated factors of cognitive frailty in older patients with lung cancer undergoing chemotherapy: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Transcriptomic Signature of Frailty in Older Patients With Cardiovascular Disease Undergoing Cardiac Surgery or TAVI.Journal of cachexia, sarcopenia and muscle · 2025Article
- Abnormalities of resting-state EEG microstates in older adults with cognitive frailty.GeroScience · 2025Article
- Cognitive frailty: a useful concept or a source of confusion? Insights from a survey of European geriatricians.BMC geriatrics · 2025Article
- Article
- Risk prediction model of physical frailty for a rural older population: a cross-sectional study in Hunan Province, China.Frontiers in public health · 2025Article
- Development and validation of a predictive model for cognitive frailty in community-dwelling older adults: a cross-sectional study.Frontiers in public health · 2025Article
- Multimorbidity patterns and cognitive frailty in adults aged over 50 years: China perspective.Frontiers in public health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review article provides an update of the empirical research on cognitive fragility conducted in the last four years. The studies retrieved were classified in four different categories. The first category includes articles relating cognitive frailty to cognitive reserve and which continue to highlight the importance of educational level. The second category includes recent research on cognitive fragility biomarkers, involving neuroimaging, metabolism and, in a novel way, microbiota. The third category includes research on how cognitive frailty is related to motor development and physical functioning, exploring e.g. the use of technology to study motor markers of cognitive frailty. Finally, in the fourth category, research clarifying the difference between reversible frailty and potentially reversible cognitive frailty has led to new interventions aimed at reducing cognitive frailty and preventing negative health outcomes. Interventions based on physical activity and multicomponent interventions are particularly emphasized. In addition, recent research explores the long-term effects of dual interventions in older adults living in nursing homes. In summary, research on cognitive frailty has increased in recent years, and applied aspects have gained importance.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.