Evidence map›Paper›PMID 34975385›Full record

ArticleFrontiers in neuroscience2021

Ebf Activates Expression of a Cholinergic Locus in a Multipolar Motor Ganglion Interneuron Subtype in

Sydney Popsuj, Alberto Stolfi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 5 citations in OpenAlex.

  1. Similarities betweeneNeuro · 2026
    Article
  2. Article
  3. Regulation of motor neuron differentiation in thebioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Development and circuitry of the tunicate larval Motor Ganglion, a putative hindbrain/spinal cord homolog.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2024
    Review
  7. A change inbioRxiv : the preprint server for biology · 2024
    Article
  8. Review
  9. Sensory cells in tunicates: insights into mechanoreceptor evolution.Frontiers in cell and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sydney PopsujSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, United States.
Alberto StolfiSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, United States.
Georgia Institute of Technology · US

Funding

Specification and maintenance of quiescent progenitor cells set aside for the biphasic life cycle of an invertebrate chordateR01GM143326 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI STOLFI, ALBERTO · 2021 to 2024
$1.3M
NIGMS NIH HHS R01 GM143326
6 · The paper itself

Abstract

Conserved transcription factors termed "terminal selectors" regulate neuronal sub-type specification and differentiation through combinatorial transcriptional regulation of terminal differentiation genes. The unique combinations of terminal differentiation gene products in turn contribute to the functional identities of each neuron. One well-characterized terminal selector is COE (Collier/Olf/Ebf), which has been shown to activate cholinergic gene batteries in

Indexed as

acetylcholinecholinergicCionaCOEEbfmotor gangliontunicates

Identifiers

PMID34975385
PMCPMC8719597
OpenAlexW4200276734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.