Evidence map›Paper›PMID 34975307›Full record

ArticleInternational journal of medical sciences2022

Spatiotemporal Expression Patterns of Critical Genes Involved in FGF Signaling During Morphogenesis and Odontogenesis of Deciduous Molars in Miniature Pigs.

Wenwen Guo, Xiaoyu Lin, Ran Zhang, Lei Hu, Jiangyi Wang, Fu Wang, Jinsong Wang, Chunmei Zhang, Xiaoshan Wu, Songlin Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Tooth regeneration in animals. A systematic review.Medicina oral, patologia oral y cirugia bucal · 2025
    Pooled it
  2. Article
  3. [Role of Fibroblast Growth Factor 7 in Craniomaxillofacial Development].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Wenwen GuoBeijing Laboratory of Oral Health; Capital Medical University School of Stomatology, Beijing, China.
Xiaoyu LinBeijing Laboratory of Oral Health; Capital Medical University School of Stomatology, Beijing, China.
Ran ZhangDepartment of Oral Pathology, Peking University School and Hospital of Stomatology, Beijing, China.
Lei HuBeijing Laboratory of Oral Health; Capital Medical University School of Stomatology, Beijing, China.
Jiangyi WangBeijing Laboratory of Oral Health; Capital Medical University School of Stomatology, Beijing, China.
Fu WangBeijing Laboratory of Oral Health; Capital Medical University School of Stomatology, Beijing, China.
Jinsong WangBeijing Laboratory of Oral Health; Capital Medical University School of Stomatology, Beijing, China.
Chunmei ZhangBeijing Laboratory of Oral Health; Capital Medical University School of Stomatology, Beijing, China.
Xiaoshan WuBeijing Laboratory of Oral Health; Capital Medical University School of Stomatology, Beijing, China.
Songlin WangBeijing Laboratory of Oral Health; Capital Medical University School of Stomatology, Beijing, China.
Capital Medical University · CNCentral South University · CNDalian Medical University · CNPeking University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fibroblast growth factor (FGF) pathway plays an important role in epithelial-mesenchymal interactions during tooth development. Nevertheless, how the ligands, receptors, and antagonists of the FGF pathway are involved in epithelial-mesenchymal interactions remains largely unknown. Miniature pigs exhibit tooth anatomy and replacement patterns like those in humans and hence can serve as large animal models. The present study investigated the spatiotemporal expression patterns of critical genes encoding FGF ligands (

Indexed as

MorphogenesisOdontogenesisAnimalsEpithelial-Mesenchymal TransitionFibroblast Growth FactorsGene Expression ProfilingGene Expression Regulation, DevelopmentalModels, AnimalMolarSignal TransductionSwineSwine, MiniatureTooth, DeciduousFibroblast Growth Factorsdeciduous molardental epitheliumdental mesenchymefibroblast growth factorminiature pigtooth development

Identifiers

PMID34975307
PMCPMC8692127
OpenAlexW4200184224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.