Evidence map›Paper›PMID 34975296›Full record

ReviewInternational journal of medical sciences2022

Changes of Migration, Immunoregulation and Osteogenic Differentiation of Mesenchymal Stem Cells in Different Stages of Inflammation.

Feng Gu, Ke Zhang, Jiangbi Li, Xiaoping Xie, Qiangqiang Wen, Zhenjiang Sui, Zilong Su, Tiecheng Yu

Abstract readReview
In one paragraph

Review in International journal of medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Feng GuDepartment of Orthopedics, First Hospital of Jilin University, Changchun 130021, Jilin, China.
Ke ZhangDepartment of Orthopedics, First Hospital of Jilin University, Changchun 130021, Jilin, China.
Jiangbi LiDepartment of Orthopedics, First Hospital of Jilin University, Changchun 130021, Jilin, China.
Xiaoping XieDepartment of Orthopedics, First Hospital of Jilin University, Changchun 130021, Jilin, China.
Qiangqiang WenDepartment of Orthopedics, First Hospital of Jilin University, Changchun 130021, Jilin, China.
Zhenjiang SuiDepartment of Orthopedics, First Hospital of Jilin University, Changchun 130021, Jilin, China.
Zilong SuDepartment of Orthopedics, First Hospital of Jilin University, Changchun 130021, Jilin, China.
Tiecheng YuDepartment of Orthopedics, First Hospital of Jilin University, Changchun 130021, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone infection has always been the focus of orthopedic research. Mesenchymal stem cells (MSCs) are the natural progenitors of osteoblasts, and the process of osteogenesis is triggered in response to different signals from the extracellular matrix. MSCs exert important functions including secretion and immune regulation and also play a key role in bone regeneration. The biological behavior of MSCs in acute and chronic inflammation, especially the transformation between acute inflammation and chronic inflammation, has aroused great interest among researchers. This paper reviews the recent literature and summarizes the behavior and biological characteristics of MSCs in acute and chronic inflammation to stimulate further research on MSCs and treatment of bone diseases.

Indexed as

Cell DifferentiationCell MovementImmunomodulationOsteogenesisAcute DiseaseBone DiseasesChronic DiseaseHumansInfectionsInflammationMesenchymal Stem CellsSignal TransductionDifferentiationImmunomodulatoryInfectionMesenchymal Stem Cells

Identifiers

PMID34975296
PMCPMC8692114

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.