Evidence map›Paper›PMID 34975291›Full record

ReviewCurrent genomics2021

Engineering Resistance Against Viruses in Field Crops Using CRISPR- Cas9.

Vidya R Hinge, Rahul L Chavhan, Sandeep P Kale, Penna Suprasanna, Ulhas S Kadam

Open access · greenAbstract readReview
In one paragraph

Review in Current genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Strategies for plant-virus disease management from gene editing to nanotechnology.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. CRISPR/Cas9-mediated gene editing ofFrontiers in plant science · 2023
    Article
  15. Transgenic Improvement for Biotic Resistance of Crops.International journal of molecular sciences · 2022
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Vidya R Hinge1Department of Plant Biotechnology, Vilasrao Deshmukh College of Agricultural Biotechnology, Latur; Vasantrao Naik Marathwada Krishi Vidyapeeth (VNMKV), Parbhani 431 402, India; 2USAID-BIRAC International Project, School of Life Sciences, S.R.T.M.U., Nanded, India; 3Nuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India; 4Max Planck Institute of Molecular Plant Physiology, Potsdam- Golm, 14476, Germany.
Rahul L Chavhan1Department of Plant Biotechnology, Vilasrao Deshmukh College of Agricultural Biotechnology, Latur; Vasantrao Naik Marathwada Krishi Vidyapeeth (VNMKV), Parbhani 431 402, India; 2USAID-BIRAC International Project, School of Life Sciences, S.R.T.M.U., Nanded, India; 3Nuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India; 4Max Planck Institute of Molecular Plant Physiology, Potsdam- Golm, 14476, Germany.
Sandeep P Kale1Department of Plant Biotechnology, Vilasrao Deshmukh College of Agricultural Biotechnology, Latur; Vasantrao Naik Marathwada Krishi Vidyapeeth (VNMKV), Parbhani 431 402, India; 2USAID-BIRAC International Project, School of Life Sciences, S.R.T.M.U., Nanded, India; 3Nuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India; 4Max Planck Institute of Molecular Plant Physiology, Potsdam- Golm, 14476, Germany.
Penna Suprasanna1Department of Plant Biotechnology, Vilasrao Deshmukh College of Agricultural Biotechnology, Latur; Vasantrao Naik Marathwada Krishi Vidyapeeth (VNMKV), Parbhani 431 402, India; 2USAID-BIRAC International Project, School of Life Sciences, S.R.T.M.U., Nanded, India; 3Nuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India; 4Max Planck Institute of Molecular Plant Physiology, Potsdam- Golm, 14476, Germany.
Ulhas S Kadam1Department of Plant Biotechnology, Vilasrao Deshmukh College of Agricultural Biotechnology, Latur; Vasantrao Naik Marathwada Krishi Vidyapeeth (VNMKV), Parbhani 431 402, India; 2USAID-BIRAC International Project, School of Life Sciences, S.R.T.M.U., Nanded, India; 3Nuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Centre, Trombay, Mumbai, 400 085, India; 4Max Planck Institute of Molecular Plant Physiology, Potsdam- Golm, 14476, Germany.
Marathwada Agricultural University · INBhabha Atomic Research Centre · INSwami Ramanand Teerth Marathwada University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food security is threatened by various biotic stresses that affect the growth and production of agricultural crops. Viral diseases have become a serious concern for crop plants as they incur huge yield losses. The enhancement of host resistance against plant viruses is a priority for the effective management of plant viral diseases. However, in the present context of the climate change scenario, plant viruses are rapidly evolving, resulting in the loss of the host resistance mechanism. Advances in genome editing techniques, such as CRISPR-Cas9 [clustered regularly interspaced palindromic repeats-CRISPR-associated 9], have been recognized as promising tools for the development of plant virus resistance. CRISPR-Cas9 genome editing tool is widely preferred due to high target specificity, simplicity, efficiency, and reproducibility. CRISPR-Cas9 based virus resistance in plants has been successfully achieved by gene targeting and cleaving the viral genome or altering the plant genome to enhance plant innate immunity. In this article, we have described the CRISPR-Cas9 system, mechanism of plant immunity against viruses and highlighted the use of the CRISPR-Cas9 system to engineer virus resistance in plants. We also discussed prospects and challenges on the use of CRISPR-Cas9-mediated plant virus resistance in crop improvement.

Indexed as

Cas9CRISPRcrop improvementfood securitygenome editingplant innate immunityplant virusRNA

Identifiers

PMID34975291
PMCPMC8640848
OpenAlexW3153867489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.