Evidence map›Paper›PMID 34975245›Full record

ArticleJournal of human reproductive sciences2021

ISAR Consensus Guidelines on Safety and Ethical Practices in

Jaideep Malhotra, Keshav Malhotra, Pankaj Talwar, Priya Kannan, Prabhakar Singh, Yogesh Kumar, Nishad Chimote, Charudutt Joshi, Sachin Bawle, R B Agarwal and 6 more

Abstract read
In one paragraph

Article in Journal of human reproductive sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. ESHRE recommendations on Good Practice in the IVF laboratory†.Human reproduction (Oxford, England) · 2026
    Guideline
  2. Pooled it
  3. Article
  4. Article
  5. Improving Fertility Treatment Documentation - A Survey.Journal of human reproductive sciences
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jaideep MalhotraManaging Director, Rainbow IVF, Agra, Uttar Pradesh, President ISAR (2019), India.
Keshav MalhotraMBBS, MCE, Chief Embryologist & Director-Rainbow IVF, Agra (Uttar Pradesh), India.
Pankaj TalwarCol (Prof), VSM, Head Medical Services, Birla Fertility and IVF, Gurgaon, India.
Priya KannanIVF Lab Director, Garbba Raksshambigai Fertility Centre, Chennai, Tamilnadu, India.
Prabhakar SinghMSc clin emb, Senior clin Embryologist, 21 Century IVF Centre, Surat Vapi Killa Pardi, Gujarat, India.
Yogesh KumarSenior Clinical Embryologist, Faculty of Medical Sciences, University of Delhi, Former Clinical Embryologist & Research Associate IVF Centre MAMC & LN Hospital Delhi, India.
Nishad ChimoteM.Sc Clinemb, Scientific Director, Vaunshdhara's Fertility Centre Pvt Ltd, Indore, Madhya Pradesh, India.
Charudutt JoshiLab Director, Genes India, The ART bank, Indore, Madhya Pradesh, India.
Sachin BawleLab Director and Clinical Embryologist, Dr. Sudha Tandon's Fertility, IVF, Endoscopy and Maternity Center, Mumbai, Maharashtra, India.
R B AgarwalDirector Ashoka Superspeciality Hospital, Senior Embryologist Ashoka Advanced IVF Unit, Raipur, Chattisgarh, India.
Saroj AgarwalScientific Director & Senior Embryologist, Renovare Health Care, Kolkata, West Bengal, India.
Ved PrakashLab Director, Southend Fertility & IVF, Delhi-NCR, Noida, UP, India.
Pooja AwasthiSr. consultant Embroyologist, Freelancer, Noida, UP, India.
Sanjay ShuklaLab Director, Baheti Hospital & Centre for Reproductive Healthcare, Jaipur; Shivani Fertility & IVF Centre, Jaipur, Rajasthan, India.
Ram PrakashEmbryology Lab Director, Omya Fertility Center, New Delhi, India.
Satish Kumar AdigaProfessor; Head, Dept. of Reproductive Science, Head, Division of Clinical Embryology, Coordinator, Centre for Fertility Preservation, Kasturba Medical College I Manipal Academy of Higher Education, Manipal, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

study questionWhat are the Safe and Ethical practices for ART applicable in INDIA? WHAT IS ALREADY KNOWN: The Indian IVF industry is booming; with mushrooming of assisted reproductive technology (ART) clinics in the country, the need for regulation is immense. The ISAR has taken up this initiative to lead the way forward in establishing practice guidelines for the safe and ethical use of ARTs in our country. These guidelines discuss the points to consider before the starting of an IVF unit, to the designing of the laboratory, the staffing pattern and experience recommendations, laboratory safety guidelines, documentation and patient traceability, gamete traceability, handling biological material, the consumables and media, and different consents and checklists and also propose key performance indicators for the Indian scenario. STUDY DESIGN SIZE DURATION: This is the report of a 2-day consensus meeting where two moderators were assigned to a group of experts to collate information on safe and ethical ivf practices in INDIA. This meeting utilised surveys, available scientific evidence and personal laboratory experience into various presentations by experts on pre-decided specific topics. PARTICIPANTS/MATERIALS SETTING

methodsExpert professionals from ISAR representing clinical and embryology fields. MAIN RESULTS AND THE ROLE OF CHANCE: The report is divided in various components including the regulations, the various requirements for an ART center, qualifications and trainings, recommendations on good practices and quality management: the report and recommendations of the expert panel reflect the discussion on each of the topics and try to lay down good practice points for labs to follow. LIMITATIONS REASONS FOR CAUTION: The recommendations are solely based on expert opinion. Future availability of data may warrant an update of the same. WIDER IMPLICATIONS OF THE

findingsThese guidelines can help labs across the country to standardise their ART services and improve clinical outcomes. STUDY FUNDING/COMPETING INTERESTS: The consensus meeting and writing of the paper was supported by funds from CooperSurgical India.

Identifiers

PMID34975245
PMCPMC8656314

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.