ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2022
Factors affecting survival in 516 dogs that underwent cholecystectomy for the treatment of gallbladder mucocele.
Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Clinical and Nutritional Management of Gallbladder Mucocele in Dogs: A Four-Case Series.Animals : an open access journal from MDPI · 2026Article
- Beyond pneumoperitoneum: technical feasibility and predictive factors for gasless laparoscopic cholecystectomy in dogs.Veterinary research communications · 2026Article
- Increased risk of gallbladder rupture and death in small-breed dogs with concurrent hypothyroidism or pancreatitis undergoing cholecystectomy for gallbladder mucoceles.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2025Article
- Gallbladder mucoceles in dogs: a novel form of acquired CFTR dysfunction causing localized cystic fibrosis-like disease.American journal of physiology. Gastrointestinal and liver physiology · 2024Article
- Acquired dysfunction of CFTR underlies cystic fibrosis-like disease of the canine gallbladder.American journal of physiology. Gastrointestinal and liver physiology · 2024Article
- MUC5AC and MUC5B expression in canine gallbladder mucocele epithelial cells.The Journal of veterinary medical science · 2023Article
- Comprehensive gene expression analysis in gallbladder mucosal epithelial cells of dogs with gallbladder mucocele.Journal of veterinary internal medicineArticle
- Concurrent hepatopathy in dogs with gallbladder mucocele: Prevalence, predictors, and impact on long-term outcome.Journal of veterinary internal medicineArticle
- Comparison of fibroblast growth factor 19 concentrations between dogs with and without gallbladder mucoceles.Journal of veterinary internal medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gallbladder mucocele (GBM) is a commonly diagnosed disease process in dogs that is associated with high morbidity and mortality if not recognized and appropriately managed. Although the exact mechanism of this disease process is not completely understood, previous studies in smaller populations of dogs have identified multiple factors that predispose to the development of GBM and affect survival. The purpose of this cross-sectional, retrospective study was to evaluate the effects of age, breed category, sex, preoperative antibiotic administration, gallbladder rupture, and a positive biliary culture in dogs that had a cholecystectomy performed for the treatment of GBM. The age (median: 11 years) and percentage of dogs that died within 14 days of cholecystectomy (16.7%) are similar to what have been reported in other studies. Gallbladder rupture and a positive biliary culture occurred in 20.4% and 12.5% of dogs, respectively. Dogs with a gallbladder rupture and positive biliary culture were 2.74 and 3.10 times more likely to die within 14 days of cholecystectomy, respectively. This contradicts a recent study that failed to find a significant association between survival and biliary culture result. Interestingly, younger age was associated with an increased occurrence of gallbladder rupture in that population. Because of the potential effect of gallbladder rupture and a biliary tract infection, abdominal imaging, biliary culture, and empirical preoperative antimicrobial therapy are recommended in dogs undergoing cholecystectomy for the treatment of GBM.
Indexed as
Identifiers
34975169PMC8682924W4206880205What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.