Evidence map›Paper›PMID 34975168›Full record

ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2022

A pilot study examining a proprietary herbal blend for the treatment of canine osteoarthritis pain.

Mary L Cardeccia, Lindsay H Elam, Kelly A Deabold, Erin L Miscioscia, Janice L Huntingford

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. A full-spectrumFrontiers in pharmacology · 2025
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mary L CardecciaAnimal Rehabilitation Facility, 8040 4th Street, Dexter, Michigan 48130, USA (Cardeccia); Colorado State University College of Veterinary Medicine and Biomedical Sciences, 300 W Drake Road, Fort Collins, Colorado 80523, USA (Elam); University of Florida, Comparative Diagnostic and Population Medicine, 2015 SW 16th Avenue, Gainesville, Florida 32608, USA (Deabold, Miscioscia); Essex Animal Hospital, 355 Talbot Street N, Essex, Ontario N8M 2W3, Canada (Huntingford).
Lindsay H ElamAnimal Rehabilitation Facility, 8040 4th Street, Dexter, Michigan 48130, USA (Cardeccia); Colorado State University College of Veterinary Medicine and Biomedical Sciences, 300 W Drake Road, Fort Collins, Colorado 80523, USA (Elam); University of Florida, Comparative Diagnostic and Population Medicine, 2015 SW 16th Avenue, Gainesville, Florida 32608, USA (Deabold, Miscioscia); Essex Animal Hospital, 355 Talbot Street N, Essex, Ontario N8M 2W3, Canada (Huntingford).
Kelly A DeaboldAnimal Rehabilitation Facility, 8040 4th Street, Dexter, Michigan 48130, USA (Cardeccia); Colorado State University College of Veterinary Medicine and Biomedical Sciences, 300 W Drake Road, Fort Collins, Colorado 80523, USA (Elam); University of Florida, Comparative Diagnostic and Population Medicine, 2015 SW 16th Avenue, Gainesville, Florida 32608, USA (Deabold, Miscioscia); Essex Animal Hospital, 355 Talbot Street N, Essex, Ontario N8M 2W3, Canada (Huntingford).
Erin L MisciosciaAnimal Rehabilitation Facility, 8040 4th Street, Dexter, Michigan 48130, USA (Cardeccia); Colorado State University College of Veterinary Medicine and Biomedical Sciences, 300 W Drake Road, Fort Collins, Colorado 80523, USA (Elam); University of Florida, Comparative Diagnostic and Population Medicine, 2015 SW 16th Avenue, Gainesville, Florida 32608, USA (Deabold, Miscioscia); Essex Animal Hospital, 355 Talbot Street N, Essex, Ontario N8M 2W3, Canada (Huntingford).
Janice L HuntingfordAnimal Rehabilitation Facility, 8040 4th Street, Dexter, Michigan 48130, USA (Cardeccia); Colorado State University College of Veterinary Medicine and Biomedical Sciences, 300 W Drake Road, Fort Collins, Colorado 80523, USA (Elam); University of Florida, Comparative Diagnostic and Population Medicine, 2015 SW 16th Avenue, Gainesville, Florida 32608, USA (Deabold, Miscioscia); Essex Animal Hospital, 355 Talbot Street N, Essex, Ontario N8M 2W3, Canada (Huntingford).
Colorado State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis is the most common joint disease in dogs. Despite the use of nonsteroidal anti-inflammatory drugs (NSAIDs), many owners seek natural therapies; either to augment the response to NSAIDs, or as a replacement. Substantial research has been directed to investigation of novel therapies. A randomized, double-blinded, controlled study was conducted to assess the efficacy of a herbal remedy for treatment of canine osteoarthritis pain. Client-owned dogs (N = 24) with osteoarthritis were enrolled between 2 veterinary hospitals. Each dog underwent veterinary and owner assessment at 0, 4, and 8 weeks, using the Canine Brief Pain Inventory and Hudson activity scale. Blood was collected for a complete blood (cell) count (CBC) and serum chemistry analysis. The product was deemed to be safe and well-tolerated at the manufacturer recommended dosage, with no significant changes seen in the CBC or serum biochemical analyses. Aside from1 dog that developed gastrointestinal upset, all other dogs tolerated the supplement without complication. The supplement did not statistically improve clinical signs in dogs based on veterinary or owner assessments of lameness. There was a treatment/time effect when assessing veterinary pain scores; however,

Indexed as

Dog DiseasesOsteoarthritisAnimalsDogsDouble-Blind MethodPainPilot Projects

Identifiers

PMID34975168
PMCPMC8682926
OpenAlexW4206857152

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.