Evidence map›Paper›PMID 34974507›Full record

ArticleCancer nursing

Financial Hardship and Quality of Life Among Patients With Advanced Cancer Receiving Outpatient Palliative Care: A Pilot Study.

Sarah M Belcher, Haerim Lee, Janet Nguyen, Kimberly Curseen, Ashima Lal, Ali John Zarrabi, Lindsay Gantz, Margaret Q Rosenzweig, Jennifer L Hill, Katherine A Yeager

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Cancer nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07410689 (SAFE.AI), which is not on this map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07410689 nanot yet recruitingnot on this map

SAFE.AI: Developing and Testing an AI-based Hybrid Chatbot for Financial Empowerment in Rural Cancer Care

TypeinterventionalSponsorUniversity of UtahRan2026 to 2027Enrolled60ConditionsCancer, Financial ToxicityArmsRule-Based Chatbot, Hybrid Chatbot
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Evaluation of financial toxicity and associated factors in female patients with breast cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
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  11. A Resilience Framework for Research in Oncology Massage Therapy.International journal of therapeutic massage & bodywork · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Sarah M BelcherAuthor Affiliations: Department of Health & Community Systems, University of Pittsburgh School of Nursing (Dr Belcher); and Hillman Cancer Center, University of Pittsburgh Medical Center (Drs Belcher and Rosenzweig), Pennsylvania; Nell Hodgson Woodruff School of Nursing (Ms Lee and Dr Yeager) and Department of Neuroscience and Behavioral Biology, Emory University (Ms Nguyen); Emory Healthcare (Drs Curseen and Zarrabi and Mss Gantz and Hill); School of Medicine, Emory University (Drs Curseen, Lal, and Zarrabi); and Grady Memorial Hospital (Dr Lal), Atlanta, Georgia; Department of Acute & Tertiary Care, University of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania (Dr Rosenzweig); and Winship Cancer Institute, Atlanta, Georgia (Dr Yeager).
Haerim Lee
Janet Nguyen
Kimberly Curseen
Ashima Lal
Ali John Zarrabi
Lindsay Gantz
Margaret Q Rosenzweig
Jennifer L Hill
Katherine A Yeager
Emory University · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHN C. BYRD · 1988 to 2026
$158.0M
NCI NIH HHS P30 CA047904
6 · The paper itself

Abstract

backgroundPatients with advanced cancer are increasingly experiencing financial hardship (FH) and associated negative health outcomes.

objectiveThe aims of this study were to describe FH and explore its relationship to quality of life (QOL) in patients with advanced cancer receiving outpatient palliative care (PC).

methodsValidated questionnaires assessed FH, QOL dimensions, symptom burden, and sociodemographic and clinical characteristics. Descriptive statistics characterized the sample and described FH. Pearson correlation and linear regression assessed relationships between FH and QOL.

resultsThe average participant (n = 78) age was 56.6 (SD, 12.2) years. Most were female (56.4%), White (50%) or Black (46.2%), and had a range of education, partner statuses, and cancer diagnoses. Median time since cancer diagnosis was 35.5 months (interquartile range, 9-57.3 months). Highest mean symptom burden scores were for pain (2.5 [SD, 1.0]) and fatigue (2.0 [SD, 1.1]), on a 0- to 3-point scale (higher score representing worse symptom burden). The median COST (COmphrehensive Score for financial Toxicity) score was 15.0 (interquartile range, 9.0-23.0). Most (70%) had some (n = 43) or extreme (n = 9) difficulty paying for basic needs. Greater than 28% (n = 21) incurred cancer-related debt. Multivariate models indicated that FH negatively affected role limitations due to physical health ( P = .008), pain ( P = .003), and emotional well-being ( P = .017) QOL dimensions.

conclusionsFinancial hardship, QOL, and symptom burden scores demonstrate need for continued support for and research among patients with advanced cancer. Data support links between FH and important QOL dimensions. Larger, longitudinal studies are needed to understand how FH affects QOL in patients with advanced cancer. IMPLICATIONS FOR PRACTICE: Proactive financial assessment and interventions are needed to support patients with advanced cancer experiencing the cumulative effects of cancer and its treatment.

Indexed as

NeoplasmsQuality of LifeFemaleFinancial StressHumansMaleMiddle AgedOutpatientsPainPalliative CarePilot ProjectsSurveys and Questionnaires

Identifiers

PMID34974507
PMCPMC11195536
OpenAlexW4205862222

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.