Evidence map›Paper›PMID 34973685›Full record

ArticleAmerican journal of surgery2022

Use of post-discharge opioid consumption patterns as a tool for evaluating opioid prescribing guidelines.

Josh Bleicher, Zachary Fender, Jordan E Johnson, Brian T Cain, Kathy Phan, Damien Powers, Guo Wei, Angela P Presson, Alvin Kwok, T Bartley Pickron and 2 more

Abstract read
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In one paragraph

Article in American journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Josh BleicherDepartment of Surgery, University of Utah, Salt Lake City, UT, USA. Electronic address: Josh.bleicher@hsc.utah.edu.
Zachary FenderDepartment of Surgery, University of Utah, Salt Lake City, UT, USA.
Jordan E JohnsonDepartment of Surgery, University of Utah, Salt Lake City, UT, USA.
Brian T CainDepartment of Surgery, University of Utah, Salt Lake City, UT, USA.
Kathy PhanDivision of Pharmacy, Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA.
Damien PowersDivision of Pharmacy, Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA.
Guo WeiDivision of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, USA.
Angela P PressonDivision of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, USA.
Alvin KwokDepartment of Surgery, University of Utah, Salt Lake City, UT, USA.
T Bartley PickronDepartment of Surgery, University of Utah, Salt Lake City, UT, USA; Department of Surgery, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Courtney L ScaifeDepartment of Surgery, University of Utah, Salt Lake City, UT, USA; Department of Surgery, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Lyen C HuangDepartment of Surgery, University of Utah, Salt Lake City, UT, USA; Department of Surgery, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
Vascular Health and Risk Factors in Children with Down SyndromeKL2TR002539 · NCATS · UNIVERSITY OF UTAH · PI MURTAUGH, MAUREEN A, NYGAARD, INGRID E · 2018 to 2022
$4.3M
NCATS NIH HHS KL2 TR002539NCATS NIH HHS UL1 TR002538
6 · The paper itself

Abstract

backgroundLeftover pills from postoperative opioid prescriptions place patients and members of their communities at risk for opioid misuse. We aimed to better understand patients' post-discharge opioid consumption patterns to inform new methods of postoperative opioid prescribing.

methodsWe assessed post-discharge opioid consumption of general surgery patients and assessed the adequacy of discharge opioid prescriptions. We then compared patient opioid consumption to a number of theoretical discharge prescriptions based on different opioid prescribing guidelines and a proposed discharge prescription based on the metric 24-h pre-discharge opioid consumption (PDOC).

results62/99 patients (62.6%) returned an opioid log book. Median 24-h PDOC was 22.5 MME (IQR 5.0-45.0) and median discharge prescription size was 15 pills (IQR:10-20). Prescriptions were adequate for 83.7% of patients. The median number of pills used was 3 (IQR:0-11) and median time to opioid cessation was 3 days (IQR:0-5). Actual prescriptions were consistent with national opioid prescribing guidelines. Prescriptions based on the formula 2 × 24-h PDOC would have decreased the number of leftover pills by 7.5 per patient.

conclusionsDespite prescribing opioids consistent with national opioid prescribing guidelines, patients still receive too many pills. Improved opioid prescribing could be accomplished by use of the formula 2 × 24-h PDOC.

Indexed as

Analgesics, OpioidPostoperative PainAftercareHumansPatient DischargePractice Patterns, Physicians'Analgesics, OpioidGeneral surgeryOpioid guidelinesOpioid prescribingOpioid stewardshipPain management

Identifiers

PMID34973685
PMCPMC9213576

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.