Evidence map›Paper›PMID 34973682›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2022

Development of a Critical Appraisal Tool (AIMRDA) for the Peer-Review of Studies Assessing the Anticancer Activity of Natural Products: A Step towards Reproducibility.

Rizwan Ahmad, Muhammad Riaz, Mohammed Aldholmi, Muhammad Asif Qureshi, Shahab Uddin, Ajaz Ahmad Bhat, Pratheeshkumar Poyil, Mukhtiar Baig, Jalal Pourahmad, Trivadi Ganesan and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. REPCAN: Guideline for REporting Population-based CANcer Registry Data.Asian Pacific journal of cancer prevention : APJCP · 2023
    Guideline
  2. Article
  3. Article
  4. ChecKAP: A Checklist for Reporting a Knowledge, Attitude, and Practice (KAP) Study.Asian Pacific journal of cancer prevention : APJCP · 2024
    Article
  5. Cytotoxicity and Apoptosis Studies of Brucein D against T24 Bladder Cancer Cells.Asian Pacific journal of cancer prevention : APJCP · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Rizwan AhmadDepartment of Natural Products and Alternative Medicine, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, P.O Box # 1982, Dammam 31441, Kingdom of Saudi Arabia.
Muhammad RiazDepartment of Pharmacy, Shaheed Benazir Bhutto University Sheringal Dir Upper Khyber Pakhtun Khwa, Pakistan.
Mohammed AldholmiDepartment of Natural Products and Alternative Medicine, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, P.O Box # 1982, Dammam 31441, Kingdom of Saudi Arabia.
Muhammad Asif QureshiDepartment of Pathology, Dow International Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Shahab UddinTranslational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Ajaz Ahmad BhatCancer Research Department, Sidra Medicine, Doha, Qatar.
Pratheeshkumar PoyilKing Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
Mukhtiar BaigKing Abdulaziz University, Jeddah, Saudi Arabia.
Jalal PourahmadDepartment of Toxicology and Pharmacology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Trivadi GanesanMedical Oncology and Clinical Research, Cancer Institute (WIA), Chennai, India.
Abdul Quaiyoom KhanTranslational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Zainab SiddiquiDepartment of Pathology, Era’s Lucknow Medical College & Hospital, India.
Maha El-DemellawyBiotechnology Research Institute (GEBRI)-SRAT-city, Egypt.
Maryam GholamalizadehCancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Dewajani PurnomosariDepartment of Histology and Cell Biology. Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Elsayed I SalimFaculty of Science, Tanta University, Tanta, Egypt, Egypt.
Seyedeh Zahra Mousavi JarrahiShahrood University of Medical Sciences, Iran.
Jian-Ye ZhangSchool of Pharmaceutical Sciences, Guangzhou Medical University.
Sammad Mohammad NejadCancer Research centre, Cancer Institute, Tehran university of Medical Sciences, Tehran, Iran.
Alireza Mosavi JarrahiDepartment of Social Medicine, Medical School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The journal of APJCP (Asian Pacific Journal of Cancer Prevention) focuses to gather relevant and up-to-date novel information's related to cancer sciences. The research methodologies and approaches adopted by the researcher are prone to variation which may be desirable in the context of novel scientific findings however, the reproducibility for these studies needs to be unified and assured. The reproducibility issues are highly concerned when preclinical studies are reported in cancer, for natural products in particular. The natural products and medicinal plants are prone to a wide variation in terms of phytochemistry and phyto-pharmacology, ultimately affecting the end results for cancer studies. Hence the need for specific guidelines to adopt a best-practice in cancer research are utmost essential. The current AIMRDA guidelines aims to develop a consensus-based tool in order to enhance the quality and assure the reproducibility of studies reporting natural products in cancer prevention. A core working committee of the experts developed an initial draft for the guidelines where more focus was kept for the inclusion of specific items not covered in previous published tools. The initial draft was peer-reviewed, experts-views provided, and improved by a scientific committee comprising of field research experts, editorial experts of different journals, and academics working in different organization worldwide. The feedback from continuous online meetings, mail communications, and webinars resulted a final draft in the shape of a checklist tool, covering the best practices related to the field of natural products research in cancer prevention and treatment. It is mandatory for the authors to read and follow the AIMRDA tool, and be aware of the good-practices to be followed in cancer research prior to any submission to APJCP. Though the tool is developed based on experts in the field, it needs to be further updated and validated in practice via implementation in the field.

Indexed as

Antineoplastic AgentsBiological ProductsEditorial PoliciesConsensusHumansPeer ReviewReproducibility of ResultsResearch DesignAntineoplastic AgentsBiological Products

Identifiers

PMID34973682
PMCPMC9080379

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.