Evidence map›Paper›PMID 34973417›Full record

ArticleGenomics, proteomics & bioinformatics2021

GranatumX: A Community-engaging, Modularized, and Flexible Webtool for Single-cell Data Analysis.

David G Garmire, Xun Zhu, Aravind Mantravadi, Qianhui Huang, Breck Yunits, Yu Liu, Thomas Wolfgruber, Olivier Poirion, Tianying Zhao, Cédric Arisdakessian and 2 more

Abstract read
In one paragraph

Article in Genomics, proteomics & bioinformatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

David G GarmireDepartment of Electrical Engineering & Computer Science, University of Michigan, Ann Arbor, MI 48109, USA.
Xun ZhuEpidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA.
Aravind MantravadiDepartment of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.
Qianhui HuangDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48105, USA.
Breck YunitsEpidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA.
Yu LiuDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48105, USA.
Thomas WolfgruberEpidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA.
Olivier PoirionEpidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA.
Tianying ZhaoMolecular Biosciences and Bioengineering Graduate Program, University of Hawaii at Manoa, Honolulu, HI 96822, USA.
Cédric ArisdakessianEpidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA; Molecular Biosciences and Bioengineering Graduate Program, University of Hawaii at Manoa, Honolulu, HI 96822, USA.
Stefan StanojevicDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48105, USA.
Lana X GarmireDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48105, USA. Electronic address: lgarmire@med.umich.edu.

Funding

Transgenic Mouse, ICSI and IVF CoreP20GM103457 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI WARD, WILLIAM S · 2012 to 2018
$12.9M
An Integrative Omics Approach to Identify Biomarkers Related to Preeclampsia and Breast Cancer RisksR01HD084633 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GARMIRE, LANA X · 2016 to 2020
$3.0M
Cancer precision medicine through spatially informative single cell image and transcriptomics data analysisR01LM012373 · NLM · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GARMIRE, LANA X · 2016 to 2024
$2.4M
DR. EPS: Drug Repurposing for Extended Patient SurvivalR01LM012907 · NLM · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GARMIRE, LANA X · 2019 to 2022
$1.0M
An Integrative Bioinformatics Approach to Study Single Cancer Cell HeterogeneityK01ES025434 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GARMIRE, LANA X · 2014 to 2018
$905k
NICHD NIH HHS R01 HD084633NIEHS NIH HHS K01 ES025434NIGMS NIH HHS P20 GM103457NLM NIH HHS R01 LM012373NLM NIH HHS R01 LM012907
6 · The paper itself

Abstract

We present GranatumX, a next-generation software environment for single-cell RNA sequencing (scRNA-seq) data analysis. GranatumX is inspired by the interactive webtool Granatum. GranatumX enables biologists to access the latest scRNA-seq bioinformatics methods in a web-based graphical environment. It also offers software developers the opportunity to rapidly promote their own tools with others in customizable pipelines. The architecture of GranatumX allows for easy inclusion of plugin modules, named Gboxes, which wrap around bioinformatics tools written in various programming languages and on various platforms. GranatumX can be run on the cloud or private servers and generate reproducible results. It is a community-engaging, flexible, and evolving software ecosystem for scRNA-seq analysis, connecting developers with bench scientists. GranatumX is freely accessible at http://garmiregroup.org/granatumx/app.

Indexed as

Data AnalysisSingle-Cell AnalysisComputational BiologyEcosystemSequence Analysis, RNASoftwareAnalysisModulePipelineSingle-cell RNA sequencingWebtool

Identifiers

PMID34973417
PMCPMC8864242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.