Evidence map›Paper›PMID 34973076›Full record

ArticleClinical rheumatology2022

Hospital admission risk stratification of patients with gout presenting to the emergency department.

Wang Han, Nur Azizah Allameen, Irwani Ibrahim, Preeti Dhanasekaran, Feng Mengling, Manjari Lahiri

Open access · hybridAbstract read
In one paragraph

Article in Clinical rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Wang HanSaw Swee Hock School of Public Health, National University Health System, National University of Singapore, 12 Science Drive 2, Singapore, 117549, Singapore.
Nur Azizah AllameenDivision of Rheumatology, Department of Medicine, National University Hospital, Singapore, Singapore.
Irwani IbrahimEmergency Medicine Department, National University Hospital, National University Health System, Singapore, Singapore.
Preeti DhanasekaranDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Feng MenglingSaw Swee Hock School of Public Health, National University Health System, National University of Singapore, 12 Science Drive 2, Singapore, 117549, Singapore. ephfm@nus.edu.sg.
Manjari LahiriDivision of Rheumatology, Department of Medicine, National University Hospital, Singapore, Singapore.
National University Health System · SGNational University Hospital · SGNational University of Singapore · SG

Funding

National Research Foundation Singapore AISG-100E-2020-055National University of Singapore R-608-000-172-133
6 · The paper itself

Abstract

To characterise gout patients at high risk of hospitalisation and to develop a web-based prognostic model to predict the likelihood of gout-related hospital admissions. This was a retrospective single-centre study of 1417 patients presenting to the emergency department (ED) with a gout flare between 2015 and 2017 with a 1-year look-back period. The dataset was randomly divided, with 80% forming the derivation and the remaining forming the validation cohort. A multivariable logistic regression model was used to determine the likelihood of hospitalisation from a gout flare in the derivation cohort. The coefficients for the variables with statistically significant adjusted odds ratios were used for the development of a web-based hospitalisation risk estimator. The performance of this risk estimator model was assessed via the area under the receiver operating characteristic curve (AUROC), calibration plot, and brier score. Patients who were hospitalised with gout tended to be older, less likely male, more likely to have had a previous hospital stay with an inpatient primary diagnosis of gout, or a previous ED visit for gout, less likely to have been prescribed standby acute gout therapy, and had a significant burden of comorbidities. In the multivariable-adjusted analyses, previous hospitalisation for gout was associated with the highest odds of gout-related admission. Early identification of patients with a high likelihood of gout-related hospitalisation using our web-based validated risk estimator model may assist to target resources to the highest risk individuals, reducing the frequency of gout-related admissions and improving the overall health-related quality of life in the long term. KEY POINTS : • We reported the characteristics of gout patients visiting a tertiary hospital in Singapore. • We developed a web-based prognostic model with non-invasive variables to predict the likelihood of gout-relatedhospital admissions.

Indexed as

GoutEmergency Service, HospitalHospitalizationHumansMaleQuality of LifeRetrospective StudiesRisk AssessmentSymptom Flare UpTertiary Care CentersClinical decision support systemsEmergency serviceGoutHospital

Identifiers

PMID34973076
PMCPMC9119890
OpenAlexW4205951725

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.