Evidence map›Paper›PMID 34972911›Full record

ArticleAdvances in experimental medicine and biology2021

Health-Related Quality of Life and Rehabilitation Costs of Patients with Amputated Limb.

Xrysoula Stouka, Pantelis Stergiannis, Evangelos Konstantinou, Theodoros Katsoulas, George Intas, Rafaella Skopa, George Fildissis

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Advances in experimental medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06493539 (A Novel Application of Closed Incision Negative Pressure Wound Therapy for the Post-Surgical Management of Lower Extremity Amputations), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06493539 phase1withdrawnnot on this mapstarted 2024, after this paper: background citation

A Novel Application of Closed Incision Negative Pressure Wound Therapy for the Post-Surgical Management of Lower Extremity Amputations: A Randomized Clinical Pilot Study

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2024 to 2025Enrolled0ConditionsWound Heal, Wound DehiscenceArmsStandard of Care group, CINPWT
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Predicting limb amputation in trauma-related necrotizing fasciitis of the extremities: insights from a 10-year cohort.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Xrysoula StoukaGeneral Trauma Hospital "KAT", Marousi, Greece.
Pantelis StergiannisGeneral Oncology Hospital "Oi Agioi Anargyroi", Kifisia, Greece.
Evangelos KonstantinouNational and Kapodistrian University of Athens, Athens, Greece.
Theodoros KatsoulasNational and Kapodistrian University of Athens, Athens, Greece.
George IntasGeneral Hospital of Nikaia "Agios Panteleimon", Nikaia, Greece. intasgeo@yahoo.gr.
Rafaella SkopaIndependent Researcher, Athens, Greece.
George FildissisNational and Kapodistrian University of Athens, Athens, Greece.
National and Kapodistrian University of Athens · GRGeneral Hospital of Attica · GRGeneral Hospital of Nikea · GRHospital Agioi Anargyroi · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was the evaluation of health-related quality of life (HRQoL) and rehabilitation costs of patients with amputated limb. MATERIALS AND

methodsThis is a cross-sectional study and the study sample, which was a sample of convenience, included 100 patients with amputated limb. The tools of the survey were the Short Form Questionnaire-36 (SF-36) and the Questionnaire used for measuring rehabilitation costs in trauma patients by Stergiannis et al.Results: The sample of the study consisted of 107 patients with amputation. HRQoL significantly increased (p < 0.001) between all-time points. According to the patients' answers, there were zero costs related to rehabilitation 1 year after the amputation. The type of edge amputation had significant impact on the rate of HRQoL increase. Rehabilitation costs increased over time during the first year. The mean (SD) rehabilitation cost was 1372 (2200) € at the first 6 months and 4774 (9109) € at the second half year. HRQoL was associated with age at all-time points and with costs of purchase of special pharmaceuticals, hospitalization, other expenses, number of medical visits, and cost of phone calls.

conclusionsThe economic costs due to the amputation need to be studied as they affect the extent to which an amputated patient can meet his new emerging needs. Therefore, future research should focus in the economic dimension of the amputation in relation with the HRQoL of these patients and their relatives, so that new health policies may be conducted.

Indexed as

AmputeesQuality of LifeAmputation, SurgicalCross-Sectional StudiesHumansSurveys and QuestionnairesAmputationHealth-related quality of lifeIncomeLimpRehabilitation costs

Identifiers

PMID34972911
OpenAlexW4206764565

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.