Evidence map›Paper›PMID 34972881›Full record

ArticleCurrent topics in microbiology and immunology2021

Interactions of Extracellular Vesicles from Pathogenic Fungi with Innate Leukocytes.

Mateus Silveira Freitas, Andre Moreira Pessoni, Carolina Coelho, Vânia Luiza Deperon Bonato, Marcio L Rodrigues, Arturo Casadevall, Fausto Almeida

Abstract read
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In one paragraph

Article in Current topics in microbiology and immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Journal of fungi (Basel, Switzerland) · 2023
    Article
  3. Review
  4. Journal of fungi (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Mateus Silveira FreitasDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil.
Andre Moreira PessoniDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil.
Carolina CoelhoMRC Centre for Medical Mycology, University of Exeter, Exeter, UK.
Vânia Luiza Deperon BonatoDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil.
Marcio L RodriguesInstituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz), Curitiba, Brazil.
Arturo CasadevallDepartment of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Fausto AlmeidaDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, SP, Brazil. fbralmeida@usp.br.
Universidade de São Paulo · BRFundação Oswaldo Cruz · BRJohns Hopkins University · USUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have shown the immunomodulatory effects of extracellular vesicles (EVs) released by pathogenic fungi. Herein, we discuss the data regarding the immunomodulatory properties of fungal EVs, but also of EVs produced by infected leukocytes. This characterizes a two-way path, in which both host and fungal EVs could coexist and play crucial roles in disease progression or protection in fungal infections. We suggest that EVs can dictate the progress of fungal diseases, and their potential as therapeutic targets.

Indexed as

Extracellular VesiclesMycosesFungiHumansLeukocytes

Identifiers

PMID34972881
OpenAlexW4205763848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.