Evidence map›Paper›PMID 34972839›Full record

ArticleScientific reports2021

Highly divergent herpesviruses in threatened river dolphins from Brazil.

Helena Exposto Novoselecki, José Luiz Catão-Dias, Ana Carolina Ewbank, Pedro Enrique Navas-Suárez, Aricia Duarte-Benvenuto, Henrique Christino Lial, Samira Costa Silva, Angélica María Sánchez-Sarmiento, Waleska Gravena, Vera Maria Ferreira da Silva and 9 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 3 countries.

Helena Exposto NovoseleckiLaboratory of Wildlife Comparative Pathology, Department of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo, SP, 05508-270, Brazil.
José Luiz Catão-DiasLaboratory of Wildlife Comparative Pathology, Department of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo, SP, 05508-270, Brazil.
Ana Carolina EwbankLaboratory of Wildlife Comparative Pathology, Department of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo, SP, 05508-270, Brazil.
Pedro Enrique Navas-SuárezLaboratory of Wildlife Comparative Pathology, Department of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo, SP, 05508-270, Brazil.
Aricia Duarte-BenvenutoLaboratory of Wildlife Comparative Pathology, Department of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo, SP, 05508-270, Brazil.
Henrique Christino LialLaboratory of Wildlife Comparative Pathology, Department of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo, SP, 05508-270, Brazil.
Samira Costa SilvaLaboratory of Wildlife Comparative Pathology, Department of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo, SP, 05508-270, Brazil.
Angélica María Sánchez-SarmientoLaboratory of Wildlife Comparative Pathology, Department of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo, SP, 05508-270, Brazil.
Waleska GravenaInstituto Nacional de Pesquisas da Amazônia, Manaus, AM, 69067-375, Brazil.
Vera Maria Ferreira da SilvaInstituto Nacional de Pesquisas da Amazônia, Manaus, AM, 69067-375, Brazil.
Vitor L CarvalhoAssociação de Pesquisa e Preservação de Ecossistemas Aquáticos, Caucaia, CE, 61627-210, Brazil.
Miriam MarmontelInstituto de Desenvolvimento Sustentável Mamirauá, Tefé, AM, 69553-225, Brazil.
Carolina P BertozziInstituto de Biociências, Universidade Estadual Paulista-UNESP, Campus do Litoral Paulista, São Vicente, SP, Brazil.
Vanessa Lanes RibeiroInstituto de Biociências, Universidade Estadual Paulista-UNESP, Campus do Litoral Paulista, São Vicente, SP, Brazil.
Rodrigo Del Rio do ValleInstituto Biopesca, Praia Grande, SP, Brazil.
Juliana MarigoLaboratory of Wildlife Comparative Pathology, Department of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo, SP, 05508-270, Brazil.
Carlos G das NevesNorwegian Veterinary Institute, Arboretveien 57, 1433, Ås, Norway.
Fernando EsperónVeterinary Department, School of Biomedical and Health Sciences, Universidad Europea de Madrid, C/Tajo S/N, Villaviciosa de Odón, 28670, Madrid, Spain.
Carlos SacristánLaboratory of Wildlife Comparative Pathology, Department of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo, SP, 05508-270, Brazil. carlosvet.sac@gmail.com.
Universidade de São Paulo · BRInstituto Biopesca · BRNational Institute of Amazonian Research · BRFundação de Estudos e Pesquisas Aquáticas · BRInstituto de Desenvolvimento Sustentável Mamirauá · BRNorwegian Veterinary Institute · NOUniversidade Estadual Paulista (Unesp) · BRUniversidad Europea de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

River dolphins are a highly threatened polyphyletic group comprised of four odontocete families: Iniidae, Pontoporiidae, Lipotidae, and Platanistidae, the first two endemic to South America. To address the knowledge gap regarding infectious agents in this cetacean group, we surveyed the presence of herpesviruses by PCR in skin and/or blood samples of live-captured Amazon (Inia geoffrensis, n = 25) and Bolivian (Inia boliviensis, n = 22) river dolphins of the Amazon basin and in selected tissue samples of franciscanas (Pontoporia blainvillei, n = 27) stranded or bycaught in southeastern Brazil. Additionally, available franciscana tissue samples were examined by histopathology. Herpesvirus DNA was amplified in 13 Bolivian river dolphins (59.1%, 95% CI 38.5-79.6%) and 14 franciscanas (51.9%, 95% CI 33.0-70.7%). All Amazon river dolphins were herpesvirus-negative. Two different herpesviruses were found in Bolivian river dolphins: a previously known gammaherpesvirus detected in blood and/or skin samples of all positive individuals and a novel alphaherpesvirus in the skin of one animal. A new gammaherpesvirus was found in several franciscana samples-the first herpesvirus recorded in Pontoporiidae. Intranuclear inclusion bodies consistent with herpesvirus were observed in the lymph node of one franciscana. The high divergence among the obtained herpesviruses and those previously described can be explained by viral-host coevolution, and by the fact that these populations are fairly isolated.

Indexed as

HerpesviridaeRiversAnimal DiseasesAnimalsBrazilDNA, ViralDolphinsHerpesviridae InfectionsImmunohistochemistryDNA, Viral

Identifiers

PMID34972839
PMCPMC8720088
OpenAlexW4205479731

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.