Evidence map›Paper›PMID 34972779›Full record

ArticleBMJ case reports2021

Lymphoma presented as dysphagia: a diagnosis hard to swallow.

Mafalda João, Mário Bento-Miranda, Elisa Gravito-Soares, Marta Gravito-Soares, Pedro Figueiredo

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 74% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mafalda JoãoGastroenterology Department, Centro Hospitalar e Universitário Coimbra, Coimbra, Portugal mafaldacaine@gmail.com.
Mário Bento-MirandaGastroenterology Department, Centro Hospitalar e Universitário Coimbra, Coimbra, Portugal.
Elisa Gravito-SoaresGastroenterology Department, Centro Hospitalar e Universitário Coimbra, Coimbra, Portugal.ORCID http://orcid.org/0000-0002-5220-8757
Marta Gravito-SoaresGastroenterology Department, Centro Hospitalar e Universitário Coimbra, Coimbra, Portugal.ORCID http://orcid.org/0000-0002-0635-2475
Pedro FigueiredoGastroenterology Department, Centro Hospitalar e Universitário Coimbra, Coimbra, Portugal.
Hospitais da Universidade de Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 18-year-old woman presented with progressive oesophageal dysphagia, weight loss and night sweats over a 6-month period. Oesophagogastroduodenoscopy revealed a diffuse luminal narrowing with normal mucosa, whose biopsies were inconclusive. A cervical and thoracic CT scan showed a thickening of the upper oesophagus, densification of the mediastinal fat, several adenopathies and a 4.3×2.4 cm mass with infiltrative appearance and heterogeneous enhancement in right cervical paravertebral location. Positron emission tomography-CT showed marked increased fluorodeoxyglucose uptake in supradiaphragmatic lymph nodes, pleuropulmonary tissue, paraspinal musculature and bone marrow. Imaging-guided and surgical incisional biopsies of the paravertebral mass were inconclusive. During hospitalisation, she developed right cervicobrachial paraesthesia. Only excisional biopsy of the mass allowed the diagnosis of high-grade B-cell lymphoma not otherwise specified, Ann Arbor stage IV-B. The patient underwent chemotherapy with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone), followed by R-EPOCH (rituximab, etoposide, prednisone, vincristine, cyclophosphamide and doxorubicin hydrochloride). Follow-up at 12 months revealed complete response.

Indexed as

Deglutition DisordersLymphoma, Large B-Cell, DiffuseAdolescentAntineoplastic Combined Chemotherapy ProtocolsCyclophosphamideDoxorubicinFemaleFluorodeoxyglucose F18HumansPositron-Emission TomographyPrednisoneRituximabVincristineCyclophosphamideDoxorubicinFluorodeoxyglucose F18PrednisoneRituximabVincristineendoscopymalignant and benign haematologyoesophagus

Identifiers

PMID34972779
PMCPMC8720956
OpenAlexW4206368883

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.