Evidence map›Paper›PMID 34972768›Full record

ArticleBMJ open2021

Using natural language processing to extract self-harm and suicidality data from a clinical sample of patients with eating disorders: a retrospective cohort study.

Charlotte Cliffe, Aida Seyedsalehi, Katerina Vardavoulia, André Bittar, Sumithra Velupillai, Hitesh Shetty, Ulrike Schmidt, Rina Dutta

Abstract read
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Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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9citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Charlotte CliffeSouth London & Maudsley, NHS Foundation Trust, London, UK charlotte.cliffe@kcl.ac.uk.ORCID 0000-0003-3906-0003
Aida SeyedsalehiInstitute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
Katerina VardavouliaInstitute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
André BittarInstitute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
Sumithra VelupillaiInstitute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
Hitesh ShettyInstitute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
Ulrike SchmidtSouth London & Maudsley, NHS Foundation Trust, London, UK.
Rina DuttaSouth London & Maudsley, NHS Foundation Trust, London, UK.ORCID 0000-0002-5614-8659

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of this study was to determine risk factors for those diagnosed with eating disorders who report self-harm and suicidality. DESIGN AND

settingThis study was a retrospective cohort study within a secondary mental health service, South London and Maudsley National Health Service Trust.

participantsAll diagnosed with an F50 diagnosis of eating disorder from January 2009 to September 2019 were included. INTERVENTION AND MEASURES: Electronic health records (EHRs) for these patients were extracted and two natural language processing tools were used to determine documentation of self-harm and suicidality in their clinical notes. These tools were validated manually for attribute agreement scores within this study.

resultsThe attribute agreements for precision of positive mentions of self-harm were 0.96 and for suicidality were 0.80; this demonstrates a 'near perfect' and 'strong' agreement and highlights the reliability of the tools in identifying the EHRs reporting self-harm or suicidality. There were 7434 patients with EHRs available and diagnosed with eating disorders included in the study from the dates January 2007 to September 2019. Of these, 4591 (61.8%) had a mention of self-harm within their records and 4764 (64.0%) had a mention of suicidality; 3899 (52.4%) had mentions of both. Patients reporting either self-harm or suicidality were more likely to have a diagnosis of anorexia nervosa (AN) (self-harm, AN OR=3.44, 95% CI 1.05 to 11.3, p=0.04; suicidality, AN OR=8.20, 95% CI 2.17 to 30.1; p=0.002). They were also more likely to have a diagnosis of borderline personality disorder (p≤0.001), bipolar disorder (p<0.001) or substance misuse disorder (p<0.001).

conclusionA high percentage of patients (>60%) diagnosed with eating disorders report either self-harm or suicidal thoughts. Relative to other eating disorders, those diagnosed with AN were more likely to report either self-harm or suicidal thoughts. Psychiatric comorbidity, in particular borderline personality disorder and substance misuse, was also associated with an increase risk in self-harm and suicidality. Therefore, risk assessment among patients diagnosed with eating disorders is crucial.

Indexed as

Feeding and Eating DisordersSelf-Injurious BehaviorSuicideHumansNatural Language ProcessingReproducibility of ResultsRetrospective StudiesState MedicineSuicidal Ideationbiotechnology & bioinformaticseating disordersepidemiologysuicide & self-harm

Identifiers

PMID34972768
PMCPMC8720985

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.