Evidence map›Paper›PMID 34972729›Full record

ArticleIn vivo (Athens, Greece)

Risk Factors for Sleep Problems Prior to Radiochemotherapy for Malignant Gliomas.

Svenja Kopelke, Troels W Kjaer, Soeren Tvilsted, Steven E Schild, Tobias Bartscht, Dirk Rades

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Svenja KopelkeDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany.
Troels W KjaerDepartment of Neurology, Zealand University Hospital, Roskilde, Denmark.
Soeren TvilstedResearch Projects and Clinical Optimization, Zealand University Hospital, Koege, Denmark.
Steven E SchildDepartment of Radiation Oncology, Mayo Clinic, Scottsdale, AZ, U.S.A.
Tobias BartschtDepartment of Hematology and Oncology, University of Lübeck, Lübeck, Germany.
Dirk RadesDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany; dirk.rades@uksh.de.
University of Lübeck · DEZealand University Hospital · DKMayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimMany patients with malignant gliomas are scheduled for radiochemotherapy, which may cause emotional distress associated with sleep problems. This study aimed to determine the prevalence of such sleep problems in these patients and identify risk factors. PATIENTS AND

methodsFifty-seven patients scheduled for radiochemotherapy for grade II-IV gliomas were retrospectively investigated for pre-treatment sleep problems. Fifteen characteristics were evaluated including temporal relation to COVID-19 pandemic, age, gender, performance status, comorbidity, (family) history of malignancies, distress score, emotional problems, physical problems, practical problems, involved sites, glioma grade, upfront surgery, and corticosteroids.

resultsNineteen patients stated pre-treatment sleep problems (prevalence=66.7%). Significant associations with sleep problems were found for female gender (p=0.023), presence of emotional problems (p=0.006), and ≥4 physical problems (p<0.001). A trend was found for distress scores ≥5 (p=0.077).

conclusionThe prevalence of sleep problems was high. Risk factors were determined that can be used to identify patients who likely benefit from psychological support.

Indexed as

COVID-19GliomaSleep Wake DisordersChemoradiotherapyFemaleHumansPandemicsRetrospective StudiesRisk FactorsSARS-CoV-2Malignant gliomaprevalenceradiochemotherapyrisk factorssleep problems

Identifiers

PMID34972729
PMCPMC8765170
OpenAlexW4205929591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.