ArticleIn vivo (Athens, Greece)
Left-sided Breast Cancer Irradiation With Deep Inspiration Breath-hold: Changes in Heart and Lung Dose in Two Periods.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Trial
- Clinical Predictors of Dosimetric Precedence for Deep Inspiratory Breath Hold Radiation Therapy for Breast Cancer.Diagnostics (Basel, Switzerland) · 2026Article
- Impact of COVID-19 vaccination on radiation-induced lung injury in breast cancer patients: a retrospective cohort study.Discover oncology · 2026Article
- Dosimetric comparison of DIBH and FB for left-sided breast cancer radiation therapy.Scientific reports · 2026Article
- Comparison of heart-sparing radiation techniques for left-sided breast cancer: DIBH combined with tangential 3D radiation vs. conventional and tangential VMAT techniques.Radiation oncology (London, England) · 2026Article
- Surface-based deep inspiration breath-hold radiotherapy in left-sided breast cancer: final results from the SAVE-HEART study.ESMO open · 2024Article
- How Effective is Deep Inspiration Breath Hold in Minimizing Cardiac Doses During Hybrid Radiotherapy Treatment for Left-Sided Breast Cancer with Comprehensive Regional Nodes?Asian Pacific journal of cancer prevention : APJCP · 2024Article
- Research progress of cardiotoxicity caused by radiotherapy in breast cancer.Precision radiation oncology · 2024Review
- Correlation between the setting of gating window width and setup accuracy in left breast cancer radiotherapy based on deep inspiration breath hold.Journal of applied clinical medical physics · 2023Observational
- Screening for Coronary Artery Disease in Cancer Survivors:JACC. CardioOncology · 2023Review
- Helical Tomotherapy in Local Advanced Breast Cancer Following Mastectomy: Long-term Results and Late Toxicity Analysis.In vivo (Athens, Greece)Article
- Narrative Review: Cardiotoxicities and Cardiac-Sparing Techniques in Radiotherapy.Technology in cancer research & treatmentReview
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimPost-operative radiotherapy for breast cancer can increase cardiac disease in a dose-dependent manner. In this study we show the reduction of dose to heart and left anterior descending artery (LAD) which can be achieved by using "Deep inspiration breath-hold" (DIBH) technique. PATIENTS AND
methodsTangential 3D-planned radiation was delivered to 357 patients with left-sided breast cancer, 159 of them with the DIBH technique. A distinction was made according to fractionation scheme.
resultsThe mean heart dose was significantly reduced by DIBH from 2.64 Gy to 1.39 Gy (p<0.001). The mean dose to the LAD was significantly reduced from 5.68 Gy to 3.88 Gy (p<0.001). Mean dose and volume receiving 5, 10 and 15 Gy of ipsilateral lung were higher with both hypofractionated schedule and conventional fractionation in the DIBH group.
conclusionDIBH in left-sided breast irradiation is an effective method of reducing the radiogenic heart dose.
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