Evidence map›Paper›PMID 34972721›Full record

ArticleIn vivo (Athens, Greece)

Prevalence and Determinants of Vaginal Infection With Human Papillomavirus Among Female University Students in Vietnam.

Nguyen VAN Trang, Kiesha Prem, Zheng Quan Toh, Bui Thi Viet Ha, Pham Thi Ngoc Lan, Hau Phuc Tran, Quang Duy Pham, Nghia VAN Khuu, Mark Jit, Dung Thi Luu and 7 more

Registry-linked trialAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06681636 (A Non-inferiority Study Comparing the Immunogenicity of a Standard or an Extended Three-dose Nonavalent Human Papillomavirus Vaccine Schedule Between High-risk Women Aged 18-26 Years and Age-matched Women in the General Population), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06681636 phase2not yet recruitingnot on this map

A Non-inferiority Study Comparing the Immunogenicity of a Standard or an Extended Three-dose Nonavalent Human Papillomavirus Vaccine Schedule Between High-risk Women Aged 18-26 Years and Age-matched Women in the General Population

TypeinterventionalSponsorNational Institute of Hygiene and Epidemiology, VietnamRan2024 to 2027Enrolled300ConditionsHPV Infection, Cervical Cancer, Anogenital Cancer, Anogenital WartsArmsHuman papillomavirus 9-valent vaccine, Recombinant
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. High Burden ofMicroorganisms · 2026
    Article
  4. Article
  5. Prevalence and genotype distribution of high-riskGynecologic oncology reports · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Nguyen VAN TrangNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Kiesha PremDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, U.K.
Zheng Quan TohInfection and Immunity, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Bui Thi Viet HaDepartment of Microbiology, University of Science, Vietnam National University, Hanoi, Vietnam.
Pham Thi Ngoc LanDepartment of Natural Science, Vietnam National University of Hue, Hue, Vietnam.
Hau Phuc TranPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Quang Duy PhamPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Nghia VAN KhuuPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Mark JitDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, U.K.
Dung Thi LuuNational Institute for Control of Vaccines and Biologicals, Hanoi, Vietnam.
LE Thi Khanh LyNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
VAN CaoPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Tam-Duong LE-HaPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Kathryn BrightInfection and Immunity, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Suzanne M GarlandInfection and Immunity, Murdoch Children's Research Institute, Parkville, Victoria, Australia.
Dang Duc AnhNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam; dda@nihe.org.vn.
Kim MulhollandDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, U.K.; kim.mulholland@mcri.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimCervical cancer is the second most common malignancy among women in Vietnam, but the country is yet to introduce a national human papillomavirus (HPV) vaccine programme targeted at adolescents. We determined HPV prevalence and HPV vaccine knowledge among female university students in Vietnam. PATIENTS AND

methodsWe surveyed and screened 1,491 female university students in Hanoi, Hue, and Ho Chi Minh City for their sexual behaviours, HPV knowledge and low- and high-risk HPV infection.

resultsThe prevalence of any HPV infection and any high-risk HPV infection were 4.2% (95%CI=3.3%-5.4%) and 3.4% (95%CI=2.5%-4.4%), respectively. Being sexually active [adjusted prevalence ratio (aPR): 6.22; 95%CI=3.4-11.37] and having ever been pregnant (aPR: 4.82; 95%CI=1.93-12.04) were positively associated with high-risk HPV infection. Whilst 60% of participants had heard of HPV vaccine, only 4.6% had received the vaccine.

conclusionThe low HPV prevalence found in university students in Vietnam indicates that they can benefit from HPV vaccination, along with a well-designed HPV health promotion programme.

Indexed as

AlphapapillomavirusPapillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsAdolescentCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansPapillomaviridaePrevalenceStudentsUniversitiesVietnamPapillomavirus VaccinesfemaleHuman papillomavirusprevalenceuniversity studentsVietnam

Identifiers

PMID34972721
PMCPMC8765152

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.