ArticleIn vivo (Athens, Greece)
Amino Acids May Have Protective Effects on Salivary Glands of 5-FU-administered Mice.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 6 citations in OpenAlex.
- Hyposalivation Treatment with Non-Crosslinked Hyaluronic Acid and Amino Acids Solution-A Clinical Pilot Study.Life (Basel, Switzerland) · 2026Article
- Preclinical evidence of photobiomodulation and clarified açaí in submandibular gland protection during antineoplastic therapy: an experimental study.Lasers in medical science · 2026Article
- Protective effects of mango peel extract on carboplatin/5-fluorouracil-induced parotid gland injury and hematopoietic toxicity in male Wistar albino rats: a preclinical study.The Saudi dental journal · 2025Article
- The Protective Effects of MSC-Derived Exosomes Against Chemotherapy-Induced Parotid Gland Cytotoxicity.International journal of dentistry · 2025Article
- Orodispersible films containing chestnut shell phenolics for buccal delivery: a preclinical approach for oral mucositis prevention.Frontiers in medical technology · 2025Article
- Protective Effect of Electroacupuncture on Chemotherapy-Induced Salivary Gland Hypofunction in a Mouse Model.International journal of molecular sciences · 2023Article
- An elemental diet protects mouse salivary glands from 5-fluorouracil-induced atrophy.Oncology letters · 2022Article
- Xanthine Oxidase Inhibitor, Febuxostat Is Effective against 5-Fluorouracil-Induced Parotid Salivary Gland Injury in Rats Via Inhibition of Oxidative Stress, Inflammation and Targeting TRPC1/CHOP Signalling Pathway.Pharmaceuticals (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimThis study aimed to identify the most useful components of Elental MATERIALS AND
methodsMice (except the control group) were intraperitoneally injected with 5-FU. The mice received saline (control group and 5-FU group), dextrin (Dextrin group), amino acids (17AA group), or Elental
resultsThe volume and weight of salivary glands was higher in 17AA and Elental
conclusionAmino acids could be the most effective components of Elental
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.