Evidence map›Paper›PMID 34972710›Full record

ArticleIn vivo (Athens, Greece)

Description of a Recovery Model in Rabbits for the Study of the Late Phase of Liver Ischemia-Reperfusion Injury.

Athina G Mantelou, Argyro Zacharioudaki, George Pappas-Gogos, Apostolos Papalois, Alexandra Papoudou-Bai, Anna Goussia, Georgios K Glantzounis

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Athina G MantelouDepartment of Surgery, University Hospital of Ioannina and School of Medicine, University of Ioannina, Ioannina, Greece.
Argyro ZacharioudakiExperimental, Educational and Research Center ELPEN, Athens, Greece.
George Pappas-GogosDepartment of Surgery, University Hospital of Ioannina and School of Medicine, University of Ioannina, Ioannina, Greece.
Apostolos PapaloisExperimental, Educational and Research Center ELPEN, Athens, Greece.
Alexandra Papoudou-BaiDepartment of Pathology, Ioannina University Hospital and School of Medicine, University of Ioannina, Ioannina, Greece.
Anna GoussiaDepartment of Pathology, Ioannina University Hospital and School of Medicine, University of Ioannina, Ioannina, Greece.
Georgios K GlantzounisDepartment of Surgery, University Hospital of Ioannina and School of Medicine, University of Ioannina, Ioannina, Greece; gglantzounis@uoi.gr.
University Hospital of Ioannina · GRElpen Pharmaceutical (Greece) · GREuropean University Cyprus · CYUniversity of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimDescription of an anesthetic recovery model with endotracheal intubation in rabbits which provides metabolic stability for the study of the late phase of liver ischemia/reperfusion (I/R) injury. MATERIALS AND

methodsTwo groups of New Zealand rabbits, n=7 in each, were used: Ischemia/reperfusion (I/R) group (45 min of partial liver ischemia/reperfusion) and no intervention (sham) group. Blood alanine aminotransferase, lactate, pH values, mean arterial pressure and pCO

resultsThe I/R group presented significantly higher levels of alanine aminotransferase (p=0.001) at 2 and 24 h, and of lactate (p=0.016) at 2 h post reperfusion. No differences were documented for pH, mean arterial pressure and pCO

conclusionThis anesthetic recovery model permitted avoidance of hypoxia and respiratory acidosis, allowing the study of the late phase of I/R injury.

Indexed as

Liver DiseasesReperfusion InjuryAlanine TransaminaseAnimalsIschemiaLiverRabbitsAlanine TransaminaseanesthesiaintubationIschemia-reperfusionliverrabbitrecovery

Identifiers

PMID34972710
PMCPMC8765142
OpenAlexW4205368600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.