Evidence map›Paper›PMID 34972695›Full record

SynthesisIn vivo (Athens, Greece)

Complications of Trans-oral Endoscopic Thyroidectomy Vestibular Approach: A Systematic Review.

Ellada Akritidou, Gerasimos Douridas, Eleftherios Spartalis, Gerasimos Tsourouflis, Dimitrios Dimitroulis, Nikolaos I Nikiteas

Abstract readSystematic Review
In one paragraph

Synthesis in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Gasless endoscopic thyroidectomyFrontiers in endocrinology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ellada AkritidouDepartment of Surgery, Thriassio General Hospital, Athens, Greece; ellasakritidou@yahoo.com.
Gerasimos DouridasDepartment of Surgery, Thriassio General Hospital, Athens, Greece.
Eleftherios SpartalisHellenic Minimally Invasive and Robotic Surgery (MIRS) Study Group, Athens, Greece.
Gerasimos TsourouflisHellenic Minimally Invasive and Robotic Surgery (MIRS) Study Group, Athens, Greece.
Dimitrios DimitroulisHellenic Minimally Invasive and Robotic Surgery (MIRS) Study Group, Athens, Greece.
Nikolaos I NikiteasHellenic Minimally Invasive and Robotic Surgery (MIRS) Study Group, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review focuses on complications linked to trans-oral endoscopic thyroidectomy via vestibular approach (TOETVA) and aimed to elucidate the procedure's initial safety profile. According to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA), Pubmed, Embase, and the Cochrane databases were screened till May 2021. Twenty-eight articles, nine cohorts and nineteen case series, met the inclusion criteria. Procedure-related complications were analyzed, the most important being hypoparathyroidism: transient (range=0.94-22.2%), permanent (range=1.33-2.22%), and recurrent laryngeal nerve injury: transient (range=1.9-8.8%) and permanent (range=0.59-1.42%). Surgical trauma related complications, the most prevalent being seroma, emphysema, and hematoma accounted for 2.91%. Null mortality was reported. Although current evolving experience indicates that TOETVA is safe and linked to acceptable complication rates, the method needs to be compared with the gold standard of traditional thyroidectomy in the context of sufficiently numbered cohorts and ultimately randomized controlled trials.

Indexed as

HypoparathyroidismThyroidectomyEndoscopyHumansIntraoperative ComplicationsMouthcomplicationsminimal invasive thyroid surgeryreviewthyroid surgeryTOETVATORTVATrans-oralvestibule

Identifiers

PMID34972695
PMCPMC8765134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.