Evidence map›Paper›PMID 34972521›Full record

Observational studyBMC cardiovascular disorders2021

Trend in survival after out-of-hospital cardiac arrest and its relationship with bystander cardiopulmonary resuscitation: a six-year prospective observational study in Beijing.

Yuling Chen, Peng Yue, Ying Wu, Jia Li, Yanni Lei, Ding Gao, Jiang Liu, Pengda Han

Abstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuling Chen *School of Nursing, Capital Medical University, No. 10, You An Men Wai Xi Tou Tiao, Fengtai District, Beijing, 100069, China.
Peng Yue *School of Nursing, Capital Medical University, No. 10, You An Men Wai Xi Tou Tiao, Fengtai District, Beijing, 100069, China.
Ying WuSchool of Nursing, Capital Medical University, No. 10, You An Men Wai Xi Tou Tiao, Fengtai District, Beijing, 100069, China. helenywu@vip.163.com.
Jia LiSchool of Nursing, Capital Medical University, No. 10, You An Men Wai Xi Tou Tiao, Fengtai District, Beijing, 100069, China.
Yanni LeiBeijing Emergency Medical Center, No. 103, Qian Men Xi Da Jie, Xicheng District, Beijing, 100031, China.
Ding GaoBeijing Emergency Medical Center, No. 103, Qian Men Xi Da Jie, Xicheng District, Beijing, 100031, China.
Jiang LiuBeijing Emergency Medical Center, No. 103, Qian Men Xi Da Jie, Xicheng District, Beijing, 100031, China.
Pengda HanBeijing Emergency Medical Center, No. 103, Qian Men Xi Da Jie, Xicheng District, Beijing, 100031, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOut-of-hospital cardiac arrest (OHCA), a global health problem with a survival rate ranging from 2 to 22% across different countries, has been a leading cause of premature death for decades. The aim of this study was to evaluate the trends of survival after OHCA over time and its relationship with bystander cardiopulmonary resuscitation (CPR), initial shockable rhythm, return of spontaneous circulation (ROSC), and survived event.

methodsIn this prospective observational study, data of OHCA patients were collected following the "Utstein style" by the Beijing, China, Emergency Medical Service (EMS) from January 2011 (data from February to June in 2011 was not collected) to October 2016. Patients who had a cardiac arrest and for whom an ambulance was dispatched were included in this study. All cases were followed up to determine hospital discharge or death. The trend of OHCA survival was analyzed using the Chi-square test. The relationship among bystander CPR, initial shockable rhythm, ROSC, survived event, and OHCA survival rate was analyzed using multivariate path analyses with maximum standard likelihood estimation.

resultsA total of 25,421 cases were transferred by the Beijing EMS; among them, 5042 (19.8%) were OHCA (median age: 78 years, interquartile range: 63-85, 60.1% male), and 484 (9.6%) received bystander CPR. The survival rate was 0.6%, which did not improve from 2012 to 2015 (P = 0.569). Overall, bystander CPR was indirectly associated with an 8.0% (β = 0.080, 95% confidence interval [CI] = 0.064-0.095, P = 0.002) increase in survival rate. The indirect effect of bystander CPR on survival rate through survived event was 6.6% (β = 0.066, 95% CI = 0.051-0.081, P = 0.002), which accounted for 82.5% (0.066 of 0.080) of the total indirect effect. With every 1 increase in survived event, the possibility of survival rate will directly increase by 53.5% (β = 0.535, 95% CI = 0.512-0.554, P = 0.003).

conclusionsThe survival rate after OHCA was low in Beijing which has not improved between 2012 and 2015. The effect of bystander CPR on survival rate was mainly mediated by survived event. Trial registration Chinese Clinical Trial Registry: ChiCTR-TRC-12002149 (2 May, 2012, retrospectively registered). http://www.chictr.org.cn/showproj.aspx?proj=7400.

Indexed as

Cardiopulmonary ResuscitationAgedAged, 80 and overBeijingFemaleHumansMaleMiddle AgedOut-of-Hospital Cardiac ArrestProspective StudiesReturn of Spontaneous CirculationRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeCardiac arrestCardiac epidemiologyCardiopulmonary resuscitationCritical carePublic healthSurvival

Identifiers

PMID34972521
PMCPMC8720208

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.