Evidence map›Paper›PMID 34971857›Full record

ArticleJournal of the neurological sciences2022

Peripheral neurological complications during COVID-19: A single center experience.

Nara Miriam Michaelson, Ashwin Malhotra, Zehui Wang, Linda Heier, Kurenai Tanji, Scott Wolfe, Alka Gupta, Daniel MacGowan

Open access · greenAbstract read
In one paragraph

Article in Journal of the neurological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Review
  5. Article
  6. Neurological manifestation in COVID-19 disease with neuroimaging studies.American journal of neurodegenerative disease · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nara Miriam MichaelsonNew York-Presbyterian Hospital/Weill Cornell Medical Center, Department of Neurology, New York, NY, United States of America. Electronic address: nam9193@nyp.org.
Ashwin MalhotraNew York-Presbyterian Hospital/Weill Cornell Medical Center, Department of Neurology, New York, NY, United States of America.
Zehui WangNew York-Presbyterian Hospital/Weill Cornell Medical Center, Department of Neurology, New York, NY, United States of America.
Linda HeierNewYork-Presbyterian Hospital/Weill Cornell Medical Center, Department of Radiology, New York, NY, United States of America.
Kurenai TanjiNewYork-Presbyterian Hospital/Columbia University Medical Center, Departments of Neurology, Pathology, and Cell Biology, New York, NY, United States of America.
Scott WolfeHospital for Special Surgery, Weill Cornell Medical College, Department of Orthopedic Surgery, New York, NY, United States of America.
Alka GuptaNewYork-Presbyterian Hospital/Weill Cornell Medical Center, Department of Medicine, New York, NY, United States of America.
Daniel MacGowanNew York-Presbyterian Hospital/Weill Cornell Medical Center, Department of Neurology, New York, NY, United States of America.
NewYork–Presbyterian Hospital · USCornell University · USColumbia University Irving Medical Center · USHospital for Special Surgery · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsWe highlight the peripheral neurologic complications of coronavirus disease 2019 (COVID-19) associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an ongoing global health emergency.

methodsWe evaluated twenty-five patients admitted to the COVID-19 Recovery Unit (CRU) at New York-Presbyterian Weill Cornell University Medical Center after intensive care hospitalization with confirmed severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), whom neurology was consulted for weakness and/or paresthesias. All patients were clinically evaluated by a neuromuscular neurologist who performed electrodiagnostic (EDX) studies when indicated. Magnetic resonance imaging (MRI) of the affected regions, along with nerve and muscle biopsies were obtained in select patients to better elucidate the underlying diagnosis.

resultsWe found fourteen out of twenty-five patients with prolonged hospitalization for COVID-19 infection to have peripheral neurological complications, identified as plexopathies, peripheral neuropathies and entrapment neuropathies. The other eleven patients were not found to have peripheral neurologic causes for their symptoms. Patients with peripheral neurological complications often exhibited more than one type of concurrently. Specifically, there were four cases of plexopathies, nine cases of entrapment neuropathies, and six cases of peripheral neuropathies, which included cranial neuropathy, sciatic neuropathy, and multiple mononeuropathies.

conclusionsWe explore the possibility that the idiopathic peripheral neurologic complications could be manifestations of the COVID-19 disease spectrum, possibly resulting from micro-thrombotic induced nerve ischemia.

Indexed as

COVID-19Nervous System DiseasesPeripheral Nervous System DiseasesCritical CareHumansSARS-CoV-2Brachial plexopathyCOVID-19Entrapment neuropathyPeripheral neuropathyRA02SARS-CoV-2

Identifiers

PMID34971857
PMCPMC8697415
OpenAlexW4200207118

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.