Evidence map›Paper›PMID 34971524›Full record

ArticleGlobal spine journal2022

Improving Assessment of Disease Severity and Strategies for Monitoring Progression in Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 4].

Lindsay Tetreault, Philip Garwood, Aref-Ali Gharooni, Alvaro Yanez Touzet, Laura Nanna-Lohkamp, Allan Martin, Jefferson Wilson, James S Harrop, James Guest, Brian K Kwon and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Global spine journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  9. Impact of frailty on short- and long-term outcomes following cervical laminoplasty for ossification of the posterior longitudinal ligament: a retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  10. Understanding degenerative cervical myelopathy in musculoskeletal practice.The Journal of manual & manipulative therapy · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 3 countries.

Lindsay TetreaultDepartment of Neurology, Langone Health, Graduate Medical Education, 5894New York University, New York, NY, USA.
Philip GarwoodGraduate Medical Education, Internal Medicine, 7938University of Toronto, Toronto, ON, Canada.
Aref-Ali GharooniNeurosurgery Unit, Department of Clinical Neuroscience, 2152University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0002-6705-1115
Alvaro Yanez Touzet5292The University of Manchester, Manchester, UK.ORCID https://orcid.org/0000-0001-9309-1885
Laura Nanna-LohkampDivision of Neurosurgery, Department of Surgery, 7938University of Toronto, Toronto, ON, Canada.
Allan MartinDepartment of Neurosurgery, 8789University of California Davis, Sacramento, CA, USA.
Jefferson WilsonDivision of Neurosurgery, Department of Surgery, 7938University of Toronto, Toronto, ON, Canada.ORCID https://orcid.org/0000-0001-5965-0305
James S HarropDepartment of Neurological Surgery, 6559Thomas Jefferson University, Philadelphia, PA, USA.
James GuestDepartment of Neurosurgery and The Miami Project to Cure Paralysis, The Miller School of Medicine, 12235University of Miami, Miami, FL, USA.
Brian K KwonVancouver Spine Surgery Institute, Department of Orthopedics, The University of British Columbia, Vancouver, BC, Canada.
James Milligan3710McMaster University Department of Family Medicine, Hamilton, ON, Canada.
Alberto Martinez ArizalaThe Miami Project to Cure Paralysis, 12235The Miller School of Medicine University of Miami, Miami, FL, USA.
K Daniel RiewDepartment of Orthopaedics, The Och Spine Hospital at New York-Presbyterian, 5798Columbia University Medical Center, New York, NY, USA.
Michael G FehlingsDivision of Neurosurgery, Department of Surgery, 7938University of Toronto, Toronto, ON, Canada.ORCID https://orcid.org/0000-0002-5722-6364
Mark R N KotterDepartment of Neurosurgery, 151895University of Cambridge, Cambridge, UK.
Sukhvinder Kalsi-RyanKITE Research Institute, University Health Network, Toronto, ON, Canada.
Benjamin M DaviesDepartment of Neurosurgery, 151895University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0003-0591-5069
University of Toronto · CAUniversity of Cambridge · GBUniversity of Miami · USColumbia University Irving Medical Center · USMcMaster University · CANYU Langone Health · USThomas Jefferson University · USUniversity Health Network · CAUniversity of British Columbia · CAUniversity of California, Davis · USUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designNarrative Review.

objectiveTo (i) discuss why assessment and monitoring of disease progression is critical in Degenerative cervical myelopathy (DCM); (ii) outline the important features of an ideal assessment tool and (iii) discuss current and novel strategies for detecting subtle deterioration in DCM.

methodsLiterature review.

resultsDegenerative cervical myelopathy is an overarching term used to describe progressive injury to the cervical spinal cord by age-related changes of the spinal axis. Based on a study by Smith et al (2020), the prevalence of DCM is approximately 2.3% and is expected to rise as the global population ages. Given the global impact of this disease, it is essential to address important knowledge gaps and prioritize areas for future investigation. As part of the AO Spine RECODE-DCM (Research Objectives and Common Data Elements for Degenerative Cervical Myelopathy) project, a priority setting partnership was initiated to increase research efficiency by identifying the top ten research priorities for DCM. One of the top ten priorities for future DCM research was: What assessment tools can be used to evaluate functional impairment, disability and quality of life in people with DCM? What instruments, tools or methods can be used or developed to monitor people with DCM for disease progression or improvement either before or after surgical treatment?

conclusionsWith the increasing prevalence of DCM, effective surveillance of this population will require both the implementation of a monitoring framework as well as the development of new assessment tools.

Indexed as

cervical spondylotic myelopathyclinician-reported outcome measuresdegenerative cervical myelopathymonitoringossification of the posterior longitudinal ligamentoutcome assessmentpatient-reported outcome measures

Identifiers

PMID34971524
PMCPMC8859700
OpenAlexW4206085039

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.