Evidence map›Paper›PMID 34971440›Full record

ArticleMikrochimica acta2021

Immunochromatographic assays based on three kinds of nanoparticles for the rapid and highly sensitive detection of tylosin and tilmicosin in eggs.

Zhiwei Liu, Jiayi Chen, Sijun Zhao, Yimeng Pang, Xing Shen, Hongtao Lei, Xiangmei Li

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

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  5. Diverse applications and development of aptamer detection technology.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhiwei Liu *Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou, 510642, China.
Jiayi Chen *Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou, 510642, China.
Sijun ZhaoChina Animal Health and Epidemiology Center, 369 Nanjing Rd, Si Fang Qu, Qingdao, 266032, China.
Yimeng PangGuangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou, 510642, China.
Xing ShenGuangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou, 510642, China.
Hongtao LeiGuangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou, 510642, China.
Xiangmei LiGuangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou, 510642, China. lixiangmei12@163.com.ORCID http://orcid.org/0000-0002-3871-8566
South China Agricultural University · CNChina Animal Health and Epidemiology Center · CN

Funding

Guangdong and Guangzhou Planned Program in Science and Technology 2017B020207010Guangdong and Guangzhou Planned Program in Science and Technology 201803020026Guangdong and Guangzhou Planned Program in Science and Technology S2013030013338National Key Research and Development Program of China 2017YFC1601205Natural Science Foundation of China 31701703Natural Science Foundation of China 31871883Shanxi Provincial Key Research and Development Program 201803D221028-1
6 · The paper itself

Abstract

Three kinds of immunochromatographic assays (ICAs) are proposed for the highly sensitive and rapid determination  of tylosin (TYL) and tilmicosin (TIM) in eggs based on colloidal gold (CG), latex microsphere (LM), and time-resolved fluorescent microsphere (TRFM). Three types of ICAs could tolerate the egg matrix via simple sample pretreatment and demonstrated high sensitivity for TYL and TIM with cut-off values of 6/6/3 μg/kg and 14/14/6 μg/kg, respectively. Furthermore, in a single-blind parallel study 20 egg samples were analyzed  by the three developed ICAs and confirmed by LC-MS/MS. The  results showed good consistency, and there were no false positive and false negative results in our three ICAs. Consequently, the proposed three ICAs offered rapid, highly sensitive, reliable, and selectable testing platforms for screening veterinary medicine or other small molecule contaminants.

Indexed as

AnimalsAnti-Bacterial AgentsChromatography, AffinityEggsFood ContaminationGold ColloidLatexMicrospheresNanoparticlesSingle-Blind MethodTylosinAnti-Bacterial AgentsGold ColloidLatextilmicosinTylosinColloidal goldImmunochromatographic assayLatex microsphereTilmicosinTime-resolved fluorescent microsphereTylosin

Identifiers

PMID34971440
OpenAlexW4206455539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.