Evidence map›Paper›PMID 34971076›Full record

ArticlePediatric blood & cancer2022

Newly identified chemotherapy-induced peripheral neuropathy in a childhood cancer survivorship clinic.

Rozalyn L Rodwin, Wilhelmenia L Ross, Jaime Rotatori, Katherine Allen, Claudia Auerbach, Lyn M Balsamo, Nina S Kadan-Lottick

Open access · greenAbstract read
In one paragraph

Article in Pediatric blood & cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Practice patterns in the diagnosis and management of chemotherapy-induced peripheral neuropathy in adolescents and young adults with cancer: a survey of oncologists.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rozalyn L RodwinSection of Pediatric Hematology/Oncology, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0002-5243-3284
Wilhelmenia L RossGeorgetown Lombardi Comprehensive Cancer Center, Washington, District of Columbia, USA.
Jaime RotatoriSection of Pediatric Hematology/Oncology, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut, USA.
Katherine AllenYale New Haven Hospital, New Haven, Connecticut, USA.
Claudia AuerbachSection of Pediatric Hematology/Oncology, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut, USA.
Lyn M BalsamoSection of Pediatric Hematology/Oncology, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0003-3703-2623
Nina S Kadan-LottickGeorgetown Lombardi Comprehensive Cancer Center, Washington, District of Columbia, USA.ORCID 0000-0002-6857-396X
Yale University · USGeorgetown University · USYale New Haven Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
The Yale Cancer Prevention and Control Training ProgramT32CA250803 · NCI · YALE UNIVERSITY · PI Melinda L Irwin, Xiaomei Ma · 2020 to 2026
$2.3M
NCATS NIH HHS UL1 TR001863NCI NIH HHS T32 CA250803
6 · The paper itself

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN), a debilitating side effect of pediatric cancer therapy, can be challenging to diagnose. We estimated the prevalence of newly identified and previously diagnosed CIPN in the regional HEROS Childhood Cancer Survivorship Clinic. From 2016 to 2018, 148 survivors (45.3% female, age 17.1 [SD 7.7] years, 81.8% in ongoing routine oncology follow-up) had their initial survivorship evaluation at an average of 7.4 (SD 6.6) years from diagnosis. Fifty-six survivors (37.8%) had CIPN, of these 46 (82.1%) were newly identified. Our findings demonstrate CIPN may be missed in routine oncology care, and new methods are needed to screen for CIPN.

Indexed as

Antineoplastic AgentsCancer SurvivorsNeoplasmsPeripheral Nervous System DiseasesAdolescentChildFemaleHumansMaleSurvivorshipAntineoplastic Agentschemotherapy-induced peripheral neuropathychildhood cancer survivorshiplate effectsplatinumvincristine

Identifiers

PMID34971076
PMCPMC8805800
OpenAlexW4206799746

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.