Evidence map›Paper›PMID 34970923›Full record

ArticleJournal of the American Heart Association2022

Effective Study: Development and Application of a Question-Driven, Time-Effective Cardiac Magnetic Resonance Scanning Protocol.

Camilla Torlasco, Silvia Castelletti, Davide Soranna, Valentina Volpato, Stefano Figliozzi, Katia Menacho, Franco Cernigliaro, Antonella Zambon, Peter Kellman, James C Moon and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Camilla TorlascoDepartment of Cardiovascular, Neural and Metabolic Sciences IRCCS Istituto Auxologico Italiano Milan Italy.ORCID 0000-0003-2382-6721
Silvia CastellettiCardiomyopathy Centre IRCCS Istituto Auxologico Italiano Milan Italy.ORCID 0000-0001-9693-4083
Davide SorannaBiostatistics Unit IRCCS Istituto Auxologico Italiano Milan Italy.
Valentina VolpatoDepartment of Cardiovascular, Neural and Metabolic Sciences IRCCS Istituto Auxologico Italiano Milan Italy.
Stefano FigliozziDepartment of Cardiovascular, Neural and Metabolic Sciences IRCCS Istituto Auxologico Italiano Milan Italy.ORCID 0000-0003-2991-1548
Katia MenachoInstitute of Cardiovascular Science University College London London UK.
Franco CernigliaroRadiodiagnostic Department IRCCS Istituto Auxologico Italiano Milan Italy.
Antonella ZambonBiostatistics Unit IRCCS Istituto Auxologico Italiano Milan Italy.
Peter KellmanNational Heart, Lung and Blood InstituteNational Institutes of Health Bethesda MD.ORCID 0000-0002-9875-6070
James C MoonInstitute of Cardiovascular Science University College London London UK.ORCID 0000-0001-8071-1491
Luigi P BadanoDepartment of Cardiovascular, Neural and Metabolic Sciences IRCCS Istituto Auxologico Italiano Milan Italy.ORCID 0000-0002-0379-3283
Gianfranco ParatiDepartment of Cardiovascular, Neural and Metabolic Sciences IRCCS Istituto Auxologico Italiano Milan Italy.ORCID 0000-0001-9402-7439
IRCCS Istituto Auxologico Italiano · ITSt Bartholomew's Hospital · GBNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Long scanning times impede cardiac magnetic resonance (CMR) clinical uptake. A "one-size-fits-all" shortened, focused protocol (eg, only function and late-gadolinium enhancement) reduces scanning time and costs, but provides less information. We developed 2 question-driven CMR and stress-CMR protocols, including tailored advanced tissue characterization, and tested their effectiveness in reducing scanning time while retaining the diagnostic performances of standard protocols. Methods and Results Eighty three consecutive patients with cardiomyopathy or ischemic heart disease underwent the tailored CMR. Each scan consisted of standard cines, late-gadolinium enhancement imaging, native T1-mapping, and extracellular volume. Fat/edema modules, right ventricle cine, and in-line quantitative perfusion mapping were performed as clinically required. Workflow was optimized to avoid gaps. Time target was <30 minutes for a CMR and <35 minutes for a stress-CMR. CMR was considered impactful when its results drove changes in diagnosis or management. Advanced tissue characterization was considered impactful when it changed the confidence level in the diagnosis. The quality of the images was assessed. A control group of 137 patients was identified among scans performed before February 2020. Compared with standard protocols, the average scan duration dropped by >30% (CMR: from 42±8 to 28±6 minutes; stress-CMR: from 50±10 to 34±6 minutes, both

Indexed as

CardiomyopathiesMyocardial IschemiaContrast MediaGadoliniumHumansMagnetic Resonance Imaging, CineMagnetic Resonance SpectroscopyPredictive Value of TestsContrast MediaGadoliniumcardiomyopathycardiovascular magnetic resonanceischemic heart diseaserapid scanningtime‐effectiveness

Identifiers

PMID34970923
PMCPMC9075206
OpenAlexW4205179090

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.