ArticleDepression and anxiety2022
The association of posttraumatic stress disorder, depression, and head injury with mid-life cognitive function in civilian women.
Article in Depression and anxiety, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Traumatic Brain Injury and Depressive Symptoms in Community-Dwelling Older Adults: A Prospective Cohort Study.Neurology · 2025Article
- Disaster-related home loss, mental health, and risk of cognitive disability: causal mediation analysis using longitudinal data of disaster survivors.American journal of epidemiology · 2025Article
- Psychological Distress and Cognitive Function in Women: Exploring Potential Mediation by Use of Opiates, Sleep Aids, or Minor Tranquilizers.Journal of women's health (2002) · 2025Article
- The link between traumatic experiences and health in late life: challenges and opportunities for US-based longitudinal aging cohorts.American journal of epidemiology · 2025Article
- Lifetime history of gestational diabetes and cognitive function in parous women in midlife.Diabetologia · 2025Article
- Lifetime History of Low Birth Weight Delivery and Cognitive Function in Middle-Aged Parous Women.Neurology · 2024Article
- Post-traumatic stress disorder symptom remission and cognition in a large cohort of civilian women.Psychological medicine · 2024Article
- Posttraumatic Stress Disorder Symptoms and Cardiovascular and Brain Health in Women.JAMA network open · 2023Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundDespite evidence linking posttraumatic stress disorder (PTSD), depression, and head injury, separately, with worse cognitive performance, investigations of their combined effects on cognition are limited in civilian women.
methodsThe Cogstate Brief Battery assessment was administered in 10,681 women from the Nurses' Health Study II cohort, mean age 64.9 years (SD = 4.6). Psychological trauma, PTSD, depression, and head injury were assessed using online questionnaires. In this cross-sectional analysis, we used linear regression models to estimate mean differences in cognition by PTSD/depression status and stratified by history of head injury.
resultsHistory of head injury was prevalent (36%), and significantly more prevalent among women with PTSD and depression (57% of women with PTSD and depression, 21% of women with no psychological trauma or depression). Compared to having no psychological trauma or depression, having combined PTSD and depression was associated with worse performance on psychomotor speed/attention (
conclusionsHead injury, like PTSD and depression, was highly prevalent in this sample of civilian women. In combination, these factors were associated with poorer performance on cognitive tasks, a possible marker of future cognitive health. Head injury should be further explored in future studies of PTSD, depression and cognition in women.
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