SynthesisPediatrics2022
Scoring Systems for Organ Dysfunction and Multiple Organ Dysfunction: The PODIUM Consensus Conference.
Synthesis in Pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07397689 (Sepsis Optimal Recognition Toolkit in Children), which is not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sepsis Optimal Recognition Toolkit in Children (SORT): An Early Recognition Tool for Children in Asia
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026.Intensive care medicine · 2026Pooled it
- Neonatal encephalopathy multiorgan scoring systems: systematic review.Frontiers in pediatrics · 2024Pooled it
- Aberrant STAT signaling and T cell dysregulation define a targetable pediatric sepsis endotype.The Journal of clinical investigation · 2026Article
- A contemporary overview of severe community-acquired bacterial infections in pediatric intensive care units.Annals of intensive care · 2026Article
- Predictors of in-hospital mortality in children with severe traumatic brain injury.SAGE open medicine · 2026Article
- Traumatic Posterior Atlantoaxial Dislocation with Intact Odontoid Treated by C2 Laminar Screw Fixation: A Case Report.International medical case reports journal · 2026Article
- Predicting In-Hospital Mortality in Pediatric Sepsis: Machine Learning Development and Multicenter Validation.Journal of inflammation research · 2026Article
- Protocol for a multi-country retrospective observational paediatric sepsis epidemiological study (SENTINEL International).BMJ open · 2025Article
- Prediction cardiovascular deterioration in a paediatric intensive care unit (PicEWS): a machine learning modelling study of routinely collected health-care data.EClinicalMedicine · 2025Article
- External Validation of the Phoenix Sepsis Score in Children With Suspected Community-Acquired Sepsis.JAMA network open · 2025Article
- Assessment of Phoenix Sepsis Score, pSOFA, PELOD-2, and PRISM III in Pediatric Intensive Care.Children (Basel, Switzerland) · 2025Article
- Pediatric sequential organ failure assessment for predicting outcomes in ECMO-bridged pediatric heart transplant recipients: experience from the largest pediatric heart transplant center in China.Frontiers in medicine · 2025Article
- New Criteria for Pediatric Sepsis: A Phoenix Rising.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024Article
- Evaluating Lactate and D-Dimer as Mortality Predictors of Paediatric Multiple Organ Dysfunction Syndrome: A Prospective Study in a Low-Middle Income Country.The Malaysian journal of medical sciences : MJMS · 2024Article
- Multiorgan Dysfunction Syndrome in Abusive and Accidental Pediatric Traumatic Brain Injury.Neurocritical care · 2024Article
- Comparison of the Recent ExPreS Score, WEANSNOW Score, and the Parsimonious HACOR Score as the Best Predictor of Weaning: An Externally Validated Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Article
- A research definition and framework for acute paediatric critical illness across resource-variable settings: a modified Delphi consensus.The Lancet. Global health · 2024Review
- Sepsis epidemiology in AustralBMJ open · 2024Article
- Quest for a Whimsical Prescient Tool!Indian journal of pediatrics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 9 institutions in 5 countries.
Funding
Abstract
contextMultiple scores exist to characterize organ dysfunction in children.
objectiveTo review the literature on multiple organ dysfunction (MOD) scoring systems to estimate severity of illness and to characterize the performance characteristics of currently used scoring tools and clinical assessments for organ dysfunction in critically ill children. DATA SOURCES: Electronic searches of PubMed and Embase were conducted from January 1992 to January 2020. STUDY SELECTION: Studies were included if they evaluated critically ill children with MOD, evaluated the performance characteristics of scoring tools for MOD, and assessed outcomes related to mortality, functional status, organ-specific outcomes, or other patient-centered outcomes. DATA EXTRACTION: Data were abstracted into a standard data extraction form by a task force member.
resultsOf 1152 unique abstracts screened, 156 full text studies were assessed including a total of 54 eligible studies. The most commonly reported scores were the Pediatric Logistic Organ Dysfunction Score (PELOD), pediatric Sequential Organ Failure Assessment score (pSOFA), Pediatric Index of Mortality (PIM), PRISM, and counts of organ dysfunction using the International Pediatric Sepsis Definition Consensus Conference. Cut-offs for specific organ dysfunction criteria, diagnostic elements included, and use of counts versus weighting varied substantially. LIMITATIONS: While scores demonstrated an increase in mortality associated with the severity and number of organ dysfunctions, the performance ranged widely.
conclusionsThe multitude of scores on organ dysfunction to assess severity of illness indicates a need for unified and data-driven organ dysfunction criteria, derived and validated in large, heterogenous international databases of critically ill children.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.