Observational studyPediatrics2022
Patterns of Organ Dysfunction in Critically Ill Children Based on PODIUM Criteria.
Observational study in Pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Respiratory-Support Phenotypes and In-Hospital Mortality in Pediatric Postprocedural Respiratory Complications.Healthcare (Basel, Switzerland) · 2026Article
- Fluid balance and acute lung injury in children and young adults receiving continuous renal replacement therapy: a report from the Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK).European journal of pediatrics · 2026Article
- A comparison of pediatric sepsis definitions based on systemic inflammatory response syndrome and Phoenix criteria: a single-center PICU retrospective study.Italian journal of pediatrics · 2026Article
- The Association Between Neighborhood Factors and Early Organ Dysfunction in Children Who Are Critically Ill: A Retrospective Cohort Study.The Journal of pediatrics · 2026Article
- Multiple organ dysfunction syndrome in pediatric colchicine poisoning: a national cohort study from Türkiye.Turkish journal of medical sciences · 2026Article
- Phoenix Sepsis Criteria in Critically Ill Children: Retrospective Validation Using a United States Nine-Center Dataset, 2012-2018.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Article
- Pediatric Sepsis Diagnosis, Management, and Sub-phenotypes.Pediatrics · 2024Article
- Pathobiology, Severity, and Risk Stratification of Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2023Review
- Prognostic factors for multi-organ dysfunction in pediatric oncology patients admitted to the pediatric intensive care unit.Frontiers in oncology · 2023Article
- Severity of illness and organ dysfunction scoring systems in pediatric critical care: The impacts on clinician's practices and the future.Frontiers in pediatrics · 2022Review
- Multiple Organ Dysfunction Interactions in Critically Ill Children.Frontiers in pediatrics · 2022Article
Corrections and comments
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Authors and funding
10 authors at 7 institutions in 1 country.
Funding
Abstract
objectivesThe goal of this study was to determine the incidence, prognostic performance, and generalizability of the Pediatric Organ Dysfunction Information Update Mandate (PODIUM) organ dysfunction criteria using electronic health record (EHR) data. Additionally, we sought to compare the performance of the PODIUM criteria with the organ dysfunction criteria proposed by the 2005 International Pediatric Sepsis Consensus Conference (IPSCC).
methodsRetrospective observational cohort study of critically ill children at 2 medical centers in the United States between 2010 and 2018. We assessed prevalence of organ dysfunction based on the PODIUM and IPSCC criteria for each 24-hour period from admission to 28 days. We studied the prognostic performance of the criteria to discriminate in-hospital mortality.
resultsOverall, 22 427 PICU admissions met inclusion criteria, and in-hospital mortality was 2.3%. The cumulative incidence of each PODIUM organ dysfunction ranged from 15% to 30%, with an in-hospital mortality of 6% to 10% for most organ systems. The number of concurrent PODIUM organ dysfunctions demonstrated good-to-excellent discrimination for in-hospital mortality (area under the curve 0.87-0.93 for day 1 through 28) and compared favorably to the IPSCC criteria (area under the curve 0.84-0.92, P < .001 to P = .06).
conclusionsWe present the first evaluation of the PODIUM organ dysfunction criteria in 2 EHR databases. The use of the PODIUM organ dysfunction criteria appears promising for epidemiologic and clinical research studies using EHR data. More studies are needed to evaluate the PODIUM criteria that are not routinely collected in structured format in EHR databases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.